Results 91 to 100 of about 25,893 (220)

Endogenously generated Dutch‐type Aβ non‐fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract BACKGROUND APPE693Q (“Dutch”) transgenic mice develop aging‐related learning deficits and accumulate endogenously generated non‐fibrillar aggregates (NFAs) of amyloid beta (Aβ) and amyloid precursor protein α‐carboxy terminal fragments. NFA‐Aβ correlates with synaptic loss and memory deficits more closely than does fibrillar Aβ.
Emilie L. Castranio, Merina Varghese, Elentina K. Argyrousi, Kuldeep Tripathi, Yong Huang, Akiko Asada, Linda Söderberg, Erin Bresnahan, David Lerner, Francesca Garretti, Hong Zhang, Jonathan van de Loo, Cheryl D. Stimpson, Ronan Talty, Charles Glabe, Efrat Levy, Minghui Wang, Marjan Ilkov, Toshiharu Suzuki, Kanae Ando, Bin Zhang, Lars Lannfelt, Brigitte Guérin, William D. Lubell, Shai Rahimipour, Dara L. Dickstein, Sam Gandy, Ottavio Arancio, Michelle E. Ehrlich   +28 more
wiley   +1 more source

Stratégia vstupu vybranej firmy na zahraničný trh

, 2007
Cieľom tejto diplomovej práce je analýza jednotlivých možností prieniku firiem na zahraničné trhy a zhodnotenie úspešnosti vstupu spoločnosti T-Mobile Czech Republic a.s. na český trh. Práca sa skladá z dvoch základných častí: I.
Trejbalová, Katarína
core   +1 more source

Gut Microbiome–Sleep Crosstalk: Mechanistic Pathways, Dysbiosis Signatures, and Microbiome‐Based Interventions

Brain and Behavior, Volume 16, Issue 6, June 2026.
Gut dysbiosis and sleep disturbances interact bidirectionally through microbial metabolites, immune activation, and neuroendocrine signaling along the gut–brain axis. Microbiome‐based interventions, including probiotics, prebiotics, synbiotics, postbiotics, and fecal microbiota transplantation, may help improve sleep quality and reduce inflammatory ...
Ghaleb Oriquat, Shaker Al‐Hasnaawei, Hayjaa Mohaisen Mousa, Malathi H, Siya Singla, Samir Sahoo, Vimal Arora, Ashish Singh Chauhan, Mehrdad Nourizadeh   +8 more
wiley   +1 more source

Integrative Transcriptomic Signature of tRNA‐Derived Fragment Targets and Lactylation‐Related Genes for Prostate Cancer Diagnosis

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Conventional diagnostic strategies for prostate cancer (PCa) are hindered by suboptimal specificity, frequently resulting in overdiagnosis and unnecessary invasive biopsies. We developed an integrative diagnostic framework based on transcriptomic signatures from tRNA‐derived fragments (tRFs), target genes, and lactylation‐related ...
Lei Wang, Xiaoxue Hu, Bixi Wang, Yaping Zhang, Jiajia Yang, Ying Wang   +5 more
wiley   +1 more source

De TRH-test tijdens de behandeling van schildklierziekten : dynamische veranderingen van de door TRH gestimuleerde TSH-afgifte

, 1979
Na de opheldering van de structuurformule van het TRH, ongeveer gelijktijdig door Schally en door Guillemin en medewerkers in 1969, en na het beschikbaar komen van TRH in synthetische vorm, is het TRH veelvuldig toegepast bij de diagnostiek van ...
Fischer, H.R.A.
core  

Case Report: Recurrent Guillain–Barré Syndrome in a 56‐Year‐Old Male

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Recurrent Guillain–Barré syndrome (GBS) is an uncommon variant of immune‐mediated polyradiculoneuropathy. We report a 56‐year‐old male who had two distinct episodes of acute inflammatory demyelinating neuropathy within the span of 3 months. The first episode presented with an episode of ascending paralysis and areflexia, with nerve conduction ...
Farah Sadiq, Shayan Nawaz, Moeez Ahmad Saeed, Fahad Bilal, Hafiza Manahil Majeed, Wasfa Shafiq, Kashaf Imtiaz, Muhammad Husnain Ahmad, Ali Gohar   +8 more
wiley   +1 more source

Mitochondrial Genome of the Indo‐Pacific Mesophotic Coral Leptoseris columna (Scleractinia: Agariciidae) Assembled Using PacBio Long‐Read Sequencing

Ecology and Evolution, Volume 16, Issue 6, June 2026.
The complete mitochondrial genome of Leptoseris columna was assembled using PacBio long read sequencing. ABSTRACT Leptoseris columna, a mesophotic coral species belonging to the family Agariciidae, is distributed throughout the Indo‐Pacific region.
Nomita Rani Adhikary, Daniel J. Barshis, J. Antonio Baeza   +2 more
wiley   +1 more source

Evolutionary Patterns of the Genes Involved in the Integrity and Segregation of Chromosomes in Sawflies (Hymenoptera: Symphyta)

Ecology and Evolution, Volume 16, Issue 6, June 2026.
This study identifies and characterizes the genes encoding cohesin and condensin complexes across Symphytan superfamilies, revealing their structural and functional roles with conserved motifs in maintaining genome stability. Phylogenetic analyses indicate that SMC genes originated from ancient duplication events, with notable gene loss (e.g., CAPG2 ...
Ayşe Rümeysa Nalça, Ertan Mahir Korkmaz   +1 more
wiley   +1 more source

Chloroplast Genome Insights of Gleditsia japonica var. velutina and Evolutionary Implications for Variation and Phylogeny in Gleditsia

Ecology and Evolution, Volume 16, Issue 6, June 2026.
This study presents the first comprehensive chloroplast genome analysis of the critically endangered G. japonica var. velutina, providing essential insights into its evolutionary divergence within the genus Gleditsia and offering a critical genomic foundation for its conservation.
Shiyu Hu, Naiwei Li, Xingjian Liu, Baocheng Wu, Yueqi Sun, Mimi Li   +5 more
wiley   +1 more source

TRH ve yeni klinik uygulama alanları

, 1996
Hipotalamustan sentez edilen TRH nöromodülatür ve nörotrop etkili bir hormondur. TRH tiroid hastalıklarında test amacıyla kullanımının yanısıra, strokta, spinoserebellar atakside, spinal kord yaralanmalarında ve kafa travmalarında, psikiyatride ...
Taşdemir, Nebahat, Haspolat, Yusuf Kenan   +1 more
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