Results 91 to 100 of about 38,461 (234)

Role of thyrotropin-releasing hormone test in re-evaluation of congenital hypothyroidism

Kaohsiung Journal of Medical Sciences, 2014
The thyrotropin-releasing hormone (TRH) test is useful for differentiating central and primary hypothyroidism, and is also valuable for diagnosing hypothyroidism. The threshold of the TRH test is usually set at 10–40 mIU/L.
Li-Min Chen, Yen-Chun Chen, Hui-Pin Hsiao, Bai-Hsiun Chen, Mei-Chyn Chao   +4 more
doaj   +1 more source

Ligand-induced selective signalling at the gonadotrophin releasing hormone receptor

, 2008
Includes abstract.Includes bibliographical references (p. 179-202).The pituitary gonadotrophin releasing hormone (GnRH) receptor regulates reproduction by activation of Gq/11 proteins.
Coetsee, Marla Catherine
core  

The role of Gai in the Gonadotropin-releasing hormone (GnRH) receptor inhibition of cell proliferation

, 2011
Includes abstract.Includes bibliographical references (leaves 72-78).The activation of Gonadotropin-releasing hormone receptor (GnRHR) by the GnRH ligand has been shown to mediate antiproliferative effects in extra-pituitary cells and in reproductive ...
Phillips, Pumza Samantha
core  

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner.

, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre, Zsolt Liposits, Liposits, Zsolt, Vastagh, Csaba, Sárvári, Miklós, Imre Farkas, Miklós Sárvári, Csaba Vastagh   +7 more
core   +1 more source

Thyrotropin Releasing Hormone Increases Intraocular Pressure Mechanism of Action [PDF]

, 2020
Intravenous injections of 1-100 ixg thyrotropin releasing hormone (TRH) in rabbits elevated intraocular pressure (IOP). The 2-5 mm Hg increase of IOP lasted for less than 2 hr. No change of pupil size was observed.
John H K Liu, PhD John Liu, Angela C Dacus, Stephen P Barrels   +3 more
core  

Demonstration of pyroglutamylpeptidase and amidase activities toward thyrotropin-releasing hormone in hamster hypothalamus extracts

, 1976
Using a radioimmunoassay method for thyrotropin-releasing hormone, the presence of thyrotropin-releasing hormone-metabolizing activity in various hamster tissues was demonstrated.
Prasad, Chandan, Peterkofsky, A.
core   +1 more source

Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria

MedComm, Volume 7, Issue 6, June 2026.
In phenylketonuria (PKU), elevated phenylalanine (Phe) increases hepatic fibroblast growth factor 21 (FGF21) and thyroid hormones, enhancing brown adipose tissue (BAT) thermogenesis in patients. Central FGF21 reproduces this phenotype in rodents via reduced hypothalamic AMP‐activated protein kinase (AMPK) activity in the ventromedial nucleus of the ...
Noemí López‐Rey, Alba Cabaleiro, María P. Pata, Marion Peyrou, Ánxela Estévez‐Salguero, Paola Fernández‐Sanmartín, Donald A. Morgan, Vitor Ferreira, Paula Sánchez‐Pintos, Cintia Folgueira, Carlos Diéguez, Adela Urisarri, Ismael González‐García, Luisa M. Seoane, Kamal Rahmouni, Francesc Villarroya, María L. Couce, Rubén Nogueiras, Miguel López   +18 more
wiley   +1 more source

A secretagogin locus of the mammalian hypothalamus controls stress hormone release

, 2015
This work was supported by the Swedish Research Council (T.Ha., T.Hö.), Hjärnfonden (T.Ha.), the Petrus and Augusta Hedlunds Foundation (T.Ha., T.Hö.), the Novo Nordisk Foundation (T.Ha., T.Hö.), Karolinska Institutet (T.Hö.), the Medical University of ...
Marc Landry, Alpár, Alán, Robert Schnell, Botting, Catherine H., André Calas, Shirran, Sally Lorna, Miklós Palkovits, Fuszard, Matthew Alexander, Wagner, Ludwig, Fuszard, Matthew, Zhang, Ming-Dong, Árpád Dobolyi, Jan Mulder, Catherine H Botting, Sten Linnarsson, Tibor Harkany, Lauren Spence, Spence, Lauren, Harkany, Tibor, Sally L Shirran, Matthew Fuszard, Uhlen, Mathias, Hökfelt, Tomas, Landry, Marc, Shirran, Sally L., Martens, Henrik, Amit Zeisel, Mathias Uhlen, Romanov, Roman A., Botting, Catherine Helen, Tomas Hökfelt, Calas, André, Oláh, Márk, Alán Alpár, Harald H Sitte, Linnarsson, Sten, Márk Oláh, Henrik Martens, Roman A Romanov, Schnell, Robert, Ming‐Dong Zhang, Ludwig Wagner, Sitte, Harald H., Uhlén, Mathias,, Dobolyi, Árpád, Zeisel, Amit, Mulder, Jan, Palkovits, Miklós   +47 more
core   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

On the conformation of thyrotropin releasing hormone [PDF]

FEBS Letters, 1974
Sievertsson, Hans, Castensson, Staffan, Bowers, Cyril Y.   +2 more
openaire   +2 more sources