Results 31 to 40 of about 320 (154)

Studying Periostin as a Diagnostic Marker in Sera of Iraqi Patients Hypothyroidism

Ibn Al-Haitham Journal for Pure and Applied Sciences
Hypothyroidism is one of the most common thyroid diseases in adults. Hypothyroidism is a condition that results from a deficiency of thyroid hormone and can range from being asymptomatic to life-threatening.
Duha Khalil Ibrahim, Layla Othman Farhan
doaj   +1 more source

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

Pediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu, Ningyi Song, Yue Zhao, Caiqi Du, Yuning Zhao, You Wu, Xiaoping Luo   +6 more
wiley   +1 more source

Dampak Klinis Thyroid-Stimulating Hormone

Jurnal Kesehatan Andalas, 2017
Thyroid-Stimulating Hormone (TSH), yang disebut juga dengan tirotropin, adalah glikoprotein yang disekresikan oleh bagian anterior dari kelenjar hipofisis. Sintesis dan sekresi dari TSH diatur oleh faktor dari hipotalamus yang didominasi oleh thyrotropin-
Eva Decroli, Alexander Kam
doaj   +1 more source

Thyrotropinoma - the case report about one of the rarest type of pituitary adenomas

Journal of Education, Health and Sport, 2022
Pituitary tumours are a significant diagnostic problem in clinical practice. Considering all the rarity of thyrotropic hormone secreting adenoma it is a diagnostic and therapeutic challenge in part due to the lack of the preoperative standards. TSH-oma,
Piotr Michał Jarosz, Zuzanna Idzik, Jakub Gołacki, Ewa Obel   +3 more
doaj   +1 more source

Factors Associated With Liver Fibrosis in Patients With Type 2 Diabetes and the Predictive Value of CHI3L1

Portal Hypertension &Cirrhosis, EarlyView.
In a retrospective cohort of 236 patients with type 2 diabetes (T2DM), metabolic dysfunction‐associated steatotic liver disease (MASLD) was common and significant fibrosis (liver stiffness measurement [LSM] ≥8 kPa) was frequently observed. Serum chitinase‐3‐like protein 1 (CHI3L1) correlated with LSM (r = 0.48) and remained an independent predictor of ...
Lixia Sun, Shuangshuang Du, Aili Fan, Jiawen Feng, Fei Wang, Jia Lian, Jie Zhang, Baoxin Qian, Qing Ye   +8 more
wiley   +1 more source

Roxadustat and transfusional iron overload induced hypothyroidism in a hemodialysis patient: a case report with a literature review

Renal Replacement Therapy
Background Although roxadustat has been reported to cause central hypothyroidism, the details of the mechanisms and clinical characteristics of patients who are prone to developing hypothyroidism with roxadustat are uncertain. Case presentation A 53-year-
Chikako Yamashita, Yuri Hirai, Toshiya Nishigaito, Kensuke Mitsumoto, Aya Mizumoto, Manabu Kawakami, Takashi Uzu   +6 more
doaj   +1 more source

Brain Delivery of Thyrotropin-Releasing Hormone via a Novel Prodrug Approach

Pharmaceutics, 2019
Using thyrotropin-releasing hormone (TRH) as a model, we explored whether synergistic combination of lipoamino acid(s) and a linker cleaved by prolyl oligopeptidase (POP) can be used as a promoiety for prodrug design for the preferential brain delivery ...
Katalin Prokai-Tatrai, Daniel L. De La Cruz, Vien Nguyen, Benjamin P. Ross, Istvan Toth, Laszlo Prokai   +5 more
doaj   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor

Frontiers in Endocrinology, 2012
Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system.
Nanthakumar eThirunarayanan, Bruce M. Raaka, Marvin C Gershengorn   +2 more
doaj   +1 more source

Clinical implications of using adrenocorticotropic hormone diagnostic cutoffs or reference intervals to diagnose pituitary pars intermedia dysfunction in mature horses

Journal of Veterinary Internal Medicine, 2021
Background Diagnosis of pituitary pars intermedia dysfunction (PPID) is problematic because of large variations in ACTH concentrations. Hypothesis/Objectives Compare the test characteristics of baseline and post–thyrotropin‐releasing hormone (TRH ...
Remona Horn, Allison J. Stewart, Karen V. Jackson, Elizabeth L. Dryburgh, Carlos E. Medina‐Torres, François‐René Bertin   +5 more
doaj   +1 more source