Results 61 to 70 of about 29,612 (294)
Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor
Frontiers in Endocrinology, 2012 Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system.
Nanthakumar eThirunarayanan +2 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2021 Background Diagnosis of pituitary pars intermedia dysfunction (PPID) is problematic because of large variations in ACTH concentrations. Hypothesis/Objectives Compare the test characteristics of baseline and post–thyrotropin‐releasing hormone (TRH ...
Remona Horn +5 more
doaj +1 more source
Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. [PDF]
, 2014 TRH is a tripeptide amide that functions as a neurotransmitter but also serves as a neurohormone that has a critical role in the central regulation of the hypothalamic-pituitary-thyroid axis.
Fekete, Csaba, Lechan, RM.
core +1 more source
International Journal of Endocrinology, 2013 Objective. The aim of this study was to investigate how the paradoxical response of GH secretion to TRH changes according to tumor volumes. Methods.
Sang Ouk Chin +6 more
doaj +1 more source
Parathyroid localization [PDF]
, 1986 Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B. +7 more
core +1 more source
Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)
Phytotherapy Research, EarlyView.ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley +1 more source
The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells [PDF]
, 1992 Thyrotropin-releasing hormone stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) in GH3 cell membranes. The stimulation of the phosphoinositide phospholipase C (PI/PLC) activity can be blocked by incubation of GH3 membranes with ...
Aragay, Anna M. +2 more
core
Effects of Obesity-Inducing Ventromedial Hypothalamic Lesions on Pulsatile Growth Hormone and Insulin Secretion: Evidence for the Existence of a Growth Hormone-Releasing Factor [PDF]
, 1983 The nature of and neural mechanisms involved in GH and insulin responses to obesity-inducing ventromedial hypothalamic (VMH) lesions, which infringed on the arcuate nucleus, were examined in freely moving chronically cannulated male rats.
Eikelboom, Rudy +1 more
core +2 more sources
Small, EarlyView.Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad +11 more
wiley +1 more source
Evidence that the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in human serum may not be secreted by the pituitary gland [PDF]
, 1997 Recent studies have revealed that TRH-like immunoreactivity (TRH-LI) in human serum is predominantly pGlu-Glu-ProNH2 (< EEP-NH2), a peptide previously found in, among others tissues, the pituitary gland of various mammalian ...
Greef, W.J. de +6 more
core +1 more source