Results 21 to 30 of about 13,578 (179)

Association of per- and polyfluoroalkyl substances with thyroid homeostasis during pregnancy in the SELMA study

Environment International, 2022
Objectives: To investigate the association of exposure to per- and polyfluoroalkyl substances (PFAS) during early pregnancy with markers of the maternal thyroid system.
Arash Derakhshan, Andreas Kortenkamp, Huan Shu, Maarten A.C. Broeren, Christian H. Lindh, Robin P. Peeters, Carl-Gustaf Bornehag, Barbara Demeneix, Tim I.M. Korevaar   +8 more
doaj   +1 more source

Challenges in interpretation of thyroid hormone test results [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2016
Introduction. In interpreting thyroid hormones results it is preferable to think of interference and changes in concentration of their carrier proteins. Outline of Cases.
Lalić Tijana, Beleslin Biljana, Savić Slavica, Stojković Mirjana, Ćirić Jasmina, Žarković Miloš   +5 more
doaj   +1 more source

Shc Is Implicated in Calreticulin-Mediated Sterile Inflammation in Alcoholic HepatitisSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Src homology and collagen (Shc) proteins are major adapters to extracellular signals, however, the regulatory role of Shc isoforms in sterile inflammatory responses in alcoholic hepatitis (AH) has not been fully investigated.
Yuan Li, Joy X. Jiang, Weiguo Fan, Sarah R. Fish, Suvarthi Das, Parul Gupta, Gergely Mozes, Lorand Vancza, Sutapa Sarkar, Koshi Kunimoto, Dongning Chen, Hyesuk Park, Dahn Clemens, Alexey Tomilov, Gino Cortopassi, Natalie J. Török   +15 more
doaj   +1 more source

Thyroid hormone and thyroid hormone nuclear receptors: History and present state of art

Endocrine Regulations, 2021
The present review traces the road leading to discovery of L-thyroxine, thyroid hormone (3,5,3´-triiodo-L-thyronine, T3) and its cognate nuclear receptors.
Brtko Julius
doaj   +1 more source

Illustration of Gut–Thyroid Axis in Alcohol Use Disorder: Interplay of Gut Dysfunction, Pro-Inflammatory Responses, and Thyroid Function

Cells, 2022
(1) Background: Heavy and chronic alcohol drinking leads to altered gut dysfunction, coupled with a pro-inflammatory state. Thyroid-associated hormones and proteins may be dysregulated by heavy and chronic alcohol intake; however, the mechanism for ...
Manasa Sagaram, Amor J. Royer, Huirong Hu, Abhas Rajhans, Ranganathan Parthasarathy, Sathya Sridevi Krishnasamy, Sri Prakash Mokshagundam, Maiying Kong, Melanie L. Schwandt, Dipendra Parajuli, Matthew C. Cave, Vatsalya Vatsalya   +11 more
doaj   +1 more source

Time-dependent changes in FT4 and FT3 levels measured using mass spectrometry after an acute ingestion of excess levothyroxine in a case with hypothyroidism

Thyroid Research, 2020
Background Thyrotoxicosis is common disorder among endocrine dysfunctions. It is not rare that the free thyroid hormone level exceeds the measurement range of immunoassay. Such extreme high concentration of free thyroid hormone is generally considered to
Yuko Ito, Satoru Suzuki, Yoshiko Matsumoto, Chiyo Ohkouchi, Satoshi Suzuki, Manabu Iwadate, Sanae Midorikawa, Susumu Yokoya, Shinichi Suzuki, Hiroki Shimura   +9 more
doaj   +1 more source

The effect of specific binding proteins on immunoassay measurements of total and free thyroid hormones and cortisol

Therapeutic Advances in Endocrinology and Metabolism, 2021
Background: Immunoassay (IA) measurements of thyroid hormones have previously given inaccurate results of triiodothyronine (T3), free triiodothyronine (FT3), and free thyroxine (FT4) when concentrations of TBG are low.
Anastasia Gant Kanegusuku, Katherine A. Araque, Hung Nguyen, Bin Wei, Saman Hosseini, Steven J. Soldin   +5 more
doaj   +1 more source

Progress and challenges in the treatment of cardiac amyloidosis: a review of the literature

ESC Heart Failure, 2021
Cardiac amyloidosis is a restrictive cardiomyopathy determined by the accumulation of amyloid, which is represented by misfolded protein fragments in the cardiac extracellular space.
Robert Daniel Adam, Daniel Coriu, Andreea Jercan, Sorina Bădeliţă, Bogdan A. Popescu, Thibaud Damy, Ruxandra Jurcuţ   +6 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Thyroid Hormone Distributor Proteins During Development in Vertebrates

Frontiers in Endocrinology, 2019
Thyroid hormones (THs) are ancient hormones that not only influence the growth, development and metabolism of vertebrates but also affect the metabolism of (at least some) bacteria. Synthesized in the thyroid gland (or follicular cells in fish not having
Sarah A. Rabah, Indra L. Gowan, Maurice Pagnin, Narin Osman, Samantha J. Richardson   +4 more
doaj   +1 more source