Results 61 to 70 of about 75,487 (358)

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Role of peripheral quantitative computed tomography in identifying disuse osteoporosis in paraplegia [PDF]

, 2009
Objective: Disuse osteoporosis is a major long-term health consequence of spinal cord injury (SCI) that still needs to be addressed. Its management in SCI should begin with accurate diagnosis, followed by targeted treatments in the most vulnerable ...
A Frotzler, A Frotzler, AA Freehafer, Alan N. McLean, B Chen, David B. Allan, ED Bruin de, HH Bolotin, HM Frost, J Rittweger, JL Ferretti, L Giangregorio, L Maimoun, M Bélanger, P Eser, P Eser, P Eser, P Frey-Rindova, P Vestergaard, S Dudley-Javoroski, S-D Jiang, Sylvie Coupaud, T Mohr   +22 more
core   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Tibial Plateau Fracture Following Low Energy Fall in the Rocky Mountains [PDF]

, 2019
Tibial plateau fractures are debilitating injuries. They can occurin younger individuals who sustain a high energy trauma or, withincreasing age, lesser degrees of trauma and underlying bone pathology such as osteoporosis, metabolic bone disease, and ...
Arvanitakis, Alexandra V., Kreienkamp, Raymond, Mian, Kerry C., Rhoades, Charles E.   +3 more
core   +2 more sources

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Comparing Outcomes Between the Over-the-Top and All-Epiphyseal Techniques for Physeal-Sparing ACL Reconstruction: A Narrative Review. [PDF]

, 2019
A variety of techniques are used for physeal-sparing anterior cruciate ligament (ACL) reconstruction; however, there is no clear consensus on the ideal surgical technique, the frequency of complications, and how to best avoid growth disturbance.
Feeley, Brian T, Pandya, Nirav K, Wong, Stephanie E   +2 more
core  

Assessment and diagnosis of acute limb compartment syndrome: A literature review [PDF]

, 2014
Background: Compartment syndrome is a collection of symptoms that signal increased pressure in the muscle compartment and results in compromised tissue perfusion.
Ali, Parveen, Santy-Tomlinson, Julie, Watson, Roger   +2 more
core   +1 more source

Stimulation of the tibial nerve: a protocol for a multicentred randomised controlled trial for urinary problems associated with Parkinson’s disease—STARTUP [PDF]

, 2020
Introduction Parkinson’s disease is the second most common chronic neurodegenerative condition with bladder dysfunction affecting up to 71%. Symptoms affect quality of life and include urgency, frequency, hesitancy, nocturia and incontinence.
Booth, Jo, Cunnington, Anne Louise, Deane, Katherine H O, Elders, Andrew, Hagen, Suzanne, Harari, Danielle, Mason, Helen, McClurg, Doreen, Panicker, Jalesh, Stratton, Susan, Walker, Richard W   +10 more
core   +3 more sources

Lateral Tibial Plateau Fracture [PDF]

Journal of Orthopaedic & Sports Physical Therapy, 2012
The patient was a 30-year-old man who was initially seen by a physical therapist for a chief complaint of left knee pain. Due to concern for a fracture, the physical therapist ordered radiographs of the left knee, which revealed a fracture of the left lateral tibial plateau. J Orthop Sports Phys Ther 2012;42(9):819. doi:10.2519/jospt.2012.0416
Warren, Flautt, Joseph, Miller, Jennifer Robyn, Ratcliff   +2 more
openaire   +2 more sources