Results 101 to 110 of about 28,270 (206)
Research and Scholarly Methods: Scoping Reviews
ABSTRACT Scoping reviews are similar to systematic reviews in that they are designed to be transparent and reproducible processes to answer a question while reducing bias. The key difference between scoping reviews and the better‐known systematic review method is the scope of the question being answered.
Jason B. Reed +2 more
wiley +1 more source
Background Microvascular blood flow (MBF) impairment in patients with lower extremity arterial disease (LEAD) is associated with more severe major adverse limb events (MALE).
Robert S. Rosenson +5 more
doaj +1 more source
Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! [PDF]
No abstract ...
Aspirin Myocardial Infarction Study Research Group +23 more
core +1 more source
Background and Purpose Network meta‐analysis (NMA) enables the simultaneous comparison of multiple treatments by combining direct and indirect evidence across a network of studies. While its application is rapidly expanding in pharmacological research and clinical guideline development, performing NMA typically requires advanced statistical knowledge ...
János Tibor Fekete +2 more
wiley +1 more source
Objective: We aimed to assess the efficacy and safety of ticagrelor compared to clopidogrel in Asian patients with acute coronary syndrome (ACS) in real-world practice.
Akhmetzhan Maratovich Galimzhanov +1 more
doaj +1 more source
P2Y12 platelet receptors: importance in percutaneous coronary intervention [PDF]
Apart from their role in hemostasis and thrombosis, platelets are involved in many other biological processes such as wound healing and angiogenesis. Percutaneous coronary intervention is a highly thrombogenic procedure inducing platelets and monocytes ...
Alves, Claudia Maria Rodrigues +5 more
core +4 more sources
ABSTRACT Clopidogrel is an antiplatelet agent widely utilized in cardiology. It is a prodrug activated in the liver by the cytochrome P450 isoform CYP2C19. Variability in the CYPC2C19 gene influences the activation and efficacy of clopidogrel. This is covered in guidelines from the Clinical Pharmacogenetics Implementation Consortium, the Dutch ...
Cinzia Dello Russo +5 more
wiley +1 more source
Effect of Ticagrelor Versus Clopidogrel on Aortic Stiffness in Patients With Coronary Artery Disease
Background We compared the acute and midterm effect of ticagrelor versus clopidogrel on aortic stiffness. Methods and Results We studied 117 patients in a randomized, assessor‐blinded, parallel‐group trial.
Charalambos Vlachopoulos +11 more
doaj +1 more source
Newer agents in antiplatelet therapy: a review. [PDF]
Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in pathophysiological conditions such as myocardial infarction, ischemia, and stroke.
Holinstat, Michael, Yeung, Jennifer
core +3 more sources
Purpose. This study aimed to explore the effects of ticagrelor (a P2Y12 receptor inhibitor) on interleukin (IL)-17 and myeloperoxidase (MPO) expression in coronary thrombus as well as on the coronary blood flow in ST-segment elevation myocardial ...
WenHua Li +8 more
doaj +1 more source

