Results 101 to 110 of about 28,270 (206)

Research and Scholarly Methods: Scoping Reviews

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 5, May 2026.
ABSTRACT Scoping reviews are similar to systematic reviews in that they are designed to be transparent and reproducible processes to answer a question while reducing bias. The key difference between scoping reviews and the better‐known systematic review method is the scope of the question being answered.
Jason B. Reed   +2 more
wiley   +1 more source

Ticagrelor improves blood viscosity-dependent microcirculatory flow in patients with lower extremity arterial disease: the Hema-kinesis clinical trial

open access: yesCardiovascular Diabetology, 2019
Background Microvascular blood flow (MBF) impairment in patients with lower extremity arterial disease (LEAD) is associated with more severe major adverse limb events (MALE).
Robert S. Rosenson   +5 more
doaj   +1 more source

Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! [PDF]

open access: yes, 2017
No abstract ...
Aspirin Myocardial Infarction Study Research Group   +23 more
core   +1 more source

NetMetaEasy: enabling rapid and user‐friendly network meta‐analysis (NMA) for comparative effectiveness research

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1814-1823, May 2026.
Background and Purpose Network meta‐analysis (NMA) enables the simultaneous comparison of multiple treatments by combining direct and indirect evidence across a network of studies. While its application is rapidly expanding in pharmacological research and clinical guideline development, performing NMA typically requires advanced statistical knowledge ...
János Tibor Fekete   +2 more
wiley   +1 more source

Ticagrelor for Asian patients with acute coronary syndrome in real-world practice: A systematic review and meta-analysis of observational studies

open access: yesIndian Heart Journal, 2019
Objective: We aimed to assess the efficacy and safety of ticagrelor compared to clopidogrel in Asian patients with acute coronary syndrome (ACS) in real-world practice.
Akhmetzhan Maratovich Galimzhanov   +1 more
doaj   +1 more source

P2Y12 platelet receptors: importance in percutaneous coronary intervention [PDF]

open access: yes, 2013
Apart from their role in hemostasis and thrombosis, platelets are involved in many other biological processes such as wound healing and angiogenesis. Percutaneous coronary intervention is a highly thrombogenic procedure inducing platelets and monocytes ...
Alves, Claudia Maria Rodrigues   +5 more
core   +4 more sources

Limited Visibility and Perception of the Clinical Relevance of Clopidogrel Pharmacogenetics in Cardiology Literature

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Clopidogrel is an antiplatelet agent widely utilized in cardiology. It is a prodrug activated in the liver by the cytochrome P450 isoform CYP2C19. Variability in the CYPC2C19 gene influences the activation and efficacy of clopidogrel. This is covered in guidelines from the Clinical Pharmacogenetics Implementation Consortium, the Dutch ...
Cinzia Dello Russo   +5 more
wiley   +1 more source

Effect of Ticagrelor Versus Clopidogrel on Aortic Stiffness in Patients With Coronary Artery Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background We compared the acute and midterm effect of ticagrelor versus clopidogrel on aortic stiffness. Methods and Results We studied 117 patients in a randomized, assessor‐blinded, parallel‐group trial.
Charalambos Vlachopoulos   +11 more
doaj   +1 more source

Newer agents in antiplatelet therapy: a review. [PDF]

open access: yes, 2012
Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in pathophysiological conditions such as myocardial infarction, ischemia, and stroke.
Holinstat, Michael, Yeung, Jennifer
core   +3 more sources

Comparison of Ticagrelor with Clopidogrel in Reducing Interleukin-17 and Myeloperoxidase Expression in Thrombus and Improving Postprocedural Coronary Flow in ST-segment Elevation Myocardial Infarction Patients

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2018
Purpose. This study aimed to explore the effects of ticagrelor (a P2Y12 receptor inhibitor) on interleukin (IL)-17 and myeloperoxidase (MPO) expression in coronary thrombus as well as on the coronary blood flow in ST-segment elevation myocardial ...
WenHua Li   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy