Investigation of Solubility Enhancement Approaches of Ticagrelor
Ticagrelor is an orally administered antiplatelet medicine, direct-acting P2Y12-receptor antagonist. Ticagrelor binds reversibly and noncompetitively to the P2Y12 receptor at a site distinct from that of the endogenous agonist adenosine diphosphate (ADP).
Ihsan A. Mohammed, Mowafaq M. Ghareeb
core +1 more source
Ticagrelor-Induced Prolongation of the QTc Interval
Background. Ticagrelor has been accepted as a class I antiplatelet agent in patients undergoing percutaneous coronary angioplasty (PTCA). There have been cases reported on ticagrelor being associated with various cardiac conduction defects.
Ahmad Najmi +3 more
core +1 more source
Does Ticagrelor Improve Endothelial Function?
Ticagrelor is a P2Y 12 receptor antagonist with proven clinical benefit in patients with acute coronary syndrome. Apart from its principal antiplatelet action, pleiotropic effects have been implicated in the clinical profile of ticagrelor, including a ...
Xanthopoulou, I. +2 more
core
OBJECTIVES The study sought to assess whether treatment with ticagrelor, as compared with prasugrel and clopidogrel, improves endothelium-dependent dilation throughout the course of the treatment and other vascular biomarkers, including systemic ...
Windecker, Stephan +13 more
core +1 more source
Ticagrelor Versus Clopidogrel or Aspirin in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Zaihan AF +4 more
europepmc +1 more source
Antithrombotic Therapy in Primary and Secondary Prevention of Coronary Artery Disease. [PDF]
Di Leo G +4 more
europepmc +1 more source
Prevalence and predictors of dyspnea in acute coronary syndrome patients receiving ticagrelor: A prospective cohort study in Iran. [PDF]
Taherkhani M +4 more
europepmc +1 more source
Bentracimab for Surgical and Perioperative Bleeding: Clinical Efficacy, Emerging Safety Concerns, and Implementation Challenges (Cost, Accessibility, and Evidence Gaps). [PDF]
Bai A +8 more
europepmc +1 more source
Risk factors of bleeding in patients with atrial fibrillation undergoing percutaneous coronary intervention: an analysis from the MANJUSRI study. [PDF]
Li Y, Lu W, Wang Y, Chen L, Ma G.
europepmc +1 more source

