Results 51 to 60 of about 14,967 (152)

Excessive Apixaban Concentrations in a Bleeding Patient Treated With Pharmacological Reversal and Extracorporal Removal—A Case Report

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
Excessive apixaban concentrations in a bleeding patient leading to impaired coagulation and treatment with pharmacological reversal and extracorporal removal. ABSTRACT In trauma, even therapeutic apixaban levels can significantly exacerbate bleeding.
Richard Felix Kraus, Johanna Rosenberger, Alexander Dejaco, Michael Paal, Christina Hart, Ralph Burkhardt, Martin Georg Kees   +6 more
wiley   +1 more source

Elevated triglyceride‐glucose index is associated with increased risk of chronic kidney disease and end‐stage renal disease in type 1 diabetes: Nationwide cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2784-2794, April 2026.
Abstract Aims Prognostic markers for microvascular complications in type 1 diabetes are needed because factors beyond hyperglycaemia contribute to this risk. The triglyceride‐glucose (TyG) index is an established marker of vascular complications in type 2 diabetes; however, its clinical significance in type 1 diabetes remains unknown.
Rosa Oh, Seohyun Kim, So Hyun Cho, Ji Yoon Kim, Myunghwa Jang, Sang Ho Park, You‐Bin Lee, Sang‐Man Jin, Kyu Yeon Hur, Gyuri Kim, Jae Hyeon Kim   +10 more
wiley   +1 more source

Comparison of P2Y12 inhibitors for mortality and stent thrombosis in patients with acute coronary syndromes: Single center study of 10 793 consecutive ‘real-world’ patients

Platelets, 2017
Three oral platelet P2Y12 inhibitors, clopidogrel, prasugrel, and ticagrelor, are available for reducing the risk of cardiovascular death and stent thrombosis in patients with acute coronary syndromes (ACS).
Rebecca Gosling, Momina Yazdani, Yasir Parviz, Ian R Hall, Ever D. Grech, Julian P Gunn, Robert F. Storey, Javaid Iqbal   +7 more
doaj   +1 more source

Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell‐Based Therapies

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Graphical presentation of stem cell‐based therapies for arterial dysfunction, endothelial repair and regeneration strategies. SMC, smooth muscle cell. ABSTRACT Arterial regeneration represents a critical frontier in cardiovascular medicine, as progressive endothelial dysfunction, maladaptive vascular smooth muscle cell (SMC) plasticity, and chronic ...
Yun‐Yu Ma, Shu‐Yao Zhu, Yi Song
wiley   +1 more source

Critical appraisal of ticagrelor in the management of acute coronary syndrome

Therapeutics and Clinical Risk Management, 2011
James J Nawarskas, Stanley S SnowdenUniversity of New Mexico College of Pharmacy, Albuquerque, NM, USAAbstract: Ticagrelor is a novel P2Y12 receptor antagonist which, like clopidogrel and prasugrel, functions by blocking adenosine diphosphate-mediated ...
Nawarskas JJ, Snowden SS
doaj  

Indobufen Dual Antiplatelet Therapy (DAPT) Versus Aspirin Dual Antiplatelet Therapy (DAPT) After Percutaneous Coronary Intervention (PCI): A Systematic Review and Meta‐Analysis

Catheterization and Cardiovascular Interventions, Volume 107, Issue 4, Page 1225-1236, March 1, 2026.
ABSTRACT Background Dual antiplatelet therapy (DAPT), which combines aspirin with a P2Y12 receptor inhibitor, is considered the standard of care for patients who have had percutaneous coronary intervention (PCI). This study aimed to compare indobufen‐based (DAPT) to aspirin‐based (DAPT) after PCI.
Omar Saeed, Abdelrahman Saeed, Osama Barakat, Abdulaziz Bawjeh, Tuğba Saka, Tasneem Mustafa Yousif, Aeshah Mohammed Adim, Muhammed Elhadi, Mamas A. Mamas   +8 more
wiley   +1 more source

Anomalous Origin of the Left Coronary System From the Right Coronary Cusp: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT The early recognition of this rare coronary anomaly using multiple imaging modalities such as CCTA provided invaluable information to better stratify the risk, clarify prognosis, and deliver the most appropriate intervention.
Cristian Castillo‐Rodriguez, Michel Juarez, Leighann Jenkins, Jason Wischmeyer, Sherif Roman, Prince Lemuel‐Ernest, Justin Price   +6 more
wiley   +1 more source

A Rare Case of Cutaneous Mucormycosis by Syncephalastrum Species in a Patient With Diabetes Mellitus: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Infections caused by Syncephalastrum species in humans are relatively rare. However, clinicians must maintain a high suspicion for it in immunocompromised patients with cutaneous mucormycosis. Prompt histopathological and microbiological investigations, combined with timely antifungal therapy and surgical intervention, are crucial to prevent ...
Iqra Maryam, Khawaja Abdul Rehman, Aymen Shafqat, Obaid Ur Rehman, Omama Ayatullah, M Rafiqul Islam, Allahdad Khan   +6 more
wiley   +1 more source

Ticagrelor alters the membrane of Staphylococcus aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance

mBio
Infections with multidrug-resistant bacteria pose a major healthcare problem which urges the need for novel treatment options. Besides its potent antiplatelet properties, ticagrelor has antibacterial activity against Gram-positive bacteria, including ...
Kirsten Leeten, Nicolas Jacques, Lidia Alejo Esquembre, Dana C. Schneider, Jan Straetener, Camilla Henriksen, Lucia Musumeci, Florence Putters, Sofia Melo, Elena Sánchez-López, Martin Giera, Noémie Penoy, Géraldine Piel, Olivier Verlaine, Ana Amoroso, Bernard Joris, Christoph J. Slavetinsky, Eric Goffin, Bernard Pirotte, Dorte Frees, Heike Brötz-Oesterhelt, Patrizio Lancellotti, Cécile Oury   +22 more
doaj   +1 more source

Assessment of Quality of Care Provided for Patients Receiving Post‐Myocardial Infarction Care at Selected Cardiac Clinics in Sulaymaniyah: Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background According to global projections, by the year 2050, ischemic heart disease will remain the leading cause of cardiovascular deaths with hypertension as a leading modifiable risk factor for mortality. Improving quality care for patients with acute myocardial infarction (MI) is associated with improved outcomes. Aims There is inadequate
Banaz Sadiq Elias, Yara Sarwar Hamid, Mende Mensa Sorato   +2 more
wiley   +1 more source