Results 101 to 110 of about 69,379 (294)

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Effects of Coinfection on the Dynamics of Two Pathogens in a Tick-Host Infection Model

Complexity, 2020
As both ticks and hosts may carry one or more pathogens, the phenomenon of coinfection of multiple tick-borne diseases becomes highly relevant and plays a key role in tick-borne disease transmission.
Bei Sun, Xue Zhang, Marco Tosato
doaj   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Co-infection with 'Candidatus Neoehrlichia mikurensis' and Borrelia afzelii in an Ixodes ricinus tick that has bitten a human in Romania

, 2014
Despite the vast importance of ticks as disease vectors, the infectious agents transmitted by ticks are still incompletely known in many areas. Here, we report for the first time the detection of the bacterium 'Candidatus Neoehrlichia mikurensis' in ...
Zaghdoudi-Allan, Nadège, Tamba, Paula, Andersson, Martin,, Chitimia, Lidia, Stefanache, Mircea, Lund University.   +5 more
core   +1 more source

Primary blood-hosts of mosquitoes are influenced by social and ecological conditions in a complex urban landscape

Parasites & Vectors, 2018
Background Temperate urban landscapes support persistent and growing populations of Culex and Aedes mosquito vectors. Large urban mosquito populations can represent a significant risk for transmission of emergent arboviral infection.
Heather Goodman, Andrea Egizi, Dina M. Fonseca, Paul T. Leisnham, Shannon L. LaDeau   +4 more
doaj   +1 more source

Detection of tick-borne infection in Morgellons disease patients by serological and molecular techniques

, 2018
Marianne J Middelveen,1 Iris Du Cruz,2 Melissa C Fesler,3 Raphael B Stricker,3 Jyotsna S Shah2 1Atkins Veterinary Services, Calgary, AB, Canada; 2IGeneX Laboratories, Palo Alto, CA, USA; 3Union Square Medical Associates, San Francisco, CA, USA Background:
Stricker RB, Middelveen MJ, Fesler MC, Du Cruz I, Shah JS   +4 more
core  

Tick-borne encephalitis as a notifiable disease : Status quo and the way forward. Report of the 17th annual meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE)

, 2015
The 17th meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE), a group of neurologists, general practicioners, clinicians, travel physicians, virologists, pediatricians, and epidemiologists, was held under the title "
ISW, TBE, Kunze, Ursula, Kunze, U, ISW-TBE   +3 more
core   +1 more source

Tick-borne encephalitis virus (TBEV) infection in pregnancy: Absence of virus transmission to the fetuses despite severe maternal disease - A case study

, 2020
Tick-borne encephalitis (TBE) is an emerging infectious disease in large parts of Europe and Asia. Whereas other members of the Flaviviridae family can harm fetal development, there are only very few reports on TBE virus (TBEV) infections during ...
Hentz, Elisabet, Louwen, Frank, Paul, Bettina, Dobler, Gerhard, Studahl, Marie,, Jahnke, Kolja, Berger, Annemarie, Buxmann, Horst, Veje, Malin,, Divé, Iris, Nürnberger, Lucas, Strzelczyk, Adam, Bergström, Tomas,   +12 more
core   +1 more source

Tick cell lines: tools for tick and tick-borne disease research [PDF]

, 2007
Over 40 cell lines are currently available from 13 ixodid and one argasid tick species. The successful isolation and propagation of several economically important tick-borne pathogens in tick cell lines has created a useful model to study interactions ...
Blouin, Edmour F., Zweygarth, Erich, Gould, Ernest A., Jongejan, Frans, Bell-Sakyi, Lesley   +4 more
core   +1 more source

Application of Viral Metagenomics for Study of Emerging and Reemerging Tick-Borne Viruses

, 2020
Ticks are important vectors for different tick-borne viruses, some of which cause diseases and death in humans, livestock, and wild animals. Tick-borne encephalitis virus, Crimean-Congo hemorrhagic fever virus, Kyasanur forest disease virus, severe fever
Johansson Wensman, Jonas,, Sveriges lantbruksuniversitet., Berg, Mikael,   +2 more
core   +1 more source