Results 111 to 120 of about 182,962 (367)
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Bayesian data assimilation provides rapid decision support for vector-borne diseases [PDF]
, 2015 Predicting the spread of vector-borne diseases in response to incursions requires knowledge of both host and vector demographics in advance of an outbreak.
Brown, Richard, Jewell, Chris
core +2 more sources
Проблемы особо опасных инфекцийThe aim of the work was to compare the main socio-demographic and eco-epidemiological parameters of tick-borne viral encephalitis, tick-borne borrelioses and tick-borne rickettsiosis.Materials and methods.
O. V. Mel’nikova +3 more
doaj +1 more source
Luciferase activity changes during the acute period of tick-borne mixed infection in children
Бюллетень сибирской медицины, 2008 The research of clinical characteristics of different tick mixed infections etiological variants in children — tick-borne encephalitis, ixodid tick-borne borreliosis, granulocytic anaplasmosis and monocytic ehrlichiosis in human in Kemerovo region showed
O. S. Pinevich +4 more
doaj +1 more source
Development of a practical framework for sustainable surveillance and control of ticks and tick-borne diseases in Africa [PDF]
, 2020 Felix Nchu +10 more
openalex +1 more source
Advanced Science, EarlyView.In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo +19 more
wiley +1 more source
Zika virus infection: a public health emergency! [PDF]
, 2017 Zika virus belongs to the family of Flaviviridae. The Flaviviridae family also includes other human pathogens like West Nile virus (WNV), Yellow fever virus (YFV), mosquito transmitted Dengue virus (DENV), Tick borne encephalitic virus (TBEV) and ...
Khan, Ramsha +2 more
core +1 more source
From Pharmacophore to Warhead: NAD+‐Targeting Triazoles as Mechanism‐Based Sirtuin Inhibitors
Angewandte Chemie, EarlyView.We report “Sirtuin Trapping Ligands” (SirTraps), mechanism‐based 1,2,3‐triazole inhibitors that hijack sirtuin (SIRT) catalysis to form covalent triazolium– or triazole–ADP‐ribose (ADPR) adducts from NAD+. These trapped intermediates stall the enzyme in an inactive state, providing a biocompatible alternative to thiocarbonyl inhibitors and a blueprint ...
Florian Friedrich +16 more
wiley +2 more sources
What Stage Are We at in the Development of Vaccines Against Tick-Borne Diseases?
VaccinesThe increasing prevalence of Lyme disease, tick-borne encephalitis (TBE), and other tick-borne infections such as Babesia, Ehrlichia, Rickettsia, and Anaplasma is a growing public health concern. Existing tick bite prevention strategies are insufficient;
Weronika Stachera +10 more
doaj +1 more source
Tick-borne pathogens and the vector potential of ticks in China
Parasites & Vectors, 2015 Ticks, as obligate blood-sucking ectoparasites, attack a broad range of vertebrates and transmit a great diversity of pathogenic microorganisms. They are considered second only to mosquitoes as vectors of human disease, and the most important vector of ...
Zhijun Yu +5 more
doaj +1 more source