AGRANULOCYTOSIS AND MACULOPAPULAR RASH AFTER TREATMENT WITH TICLOPIDINE – CASE REPORT
Background. Ticlopidine is one of inhibitors of platelet aggregation indicated for reducing the risk of thrombotic stroke in patients who have experienced thrombotic stroke, ischemic attacks, unstable angina pectoris, coronary artery stenting and ...
Janja Blatnik +4 more
doaj
Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro
.: The thienopyridine derivative ticlopidine (TCL) is an inhibitor of adenosine diphosphate-induced platelet aggregation. Combination therapy with a thienopyridine derivative and aspirin is standard after coronary stenting, although more hemorrhagic ...
Yuichi Kinoshita +9 more
doaj +1 more source
A methodological study devoted to the Mannich-like multicomponent synthesis of the antiplatelet agent (±)‑clopidogrel (7) and the ethyl ester analogue 6 is described.
Isabelle Aillaud +4 more
doaj +1 more source
Effects of Ticlopidine or Ticlopidine Plus Aspirin on Platelet Aggregation and ATP Release in Normal Volunteers: Why Aspirin Improves Ticlopidine Antiplatelet Activity [PDF]
Aspirin and ticlopidine are used to prevent arterial thrombosis. In some clinical settings ticlopidine is administered with aspirin for improving antithrombotic effect. We adminis tered aspirin (100 mg/day), ticlopidine (500mg/day), or ticlo pidine and aspirin for 7 days to healthy volunteers.
Raul Altman +3 more
openaire +3 more sources
Secondary prevention after cerebral ischaemia of presumed arterial origin: is aspirin still the touchstone? [PDF]
Patients who have had a transient ischaemic attack or nondisabling ischaemic stroke of presumed arterial origin have an annual risk of death from all vascular causes, non-fatal stroke, or non-fatal myocardial infarction that ranges between 4% and 11%
Algra, A. (Ale) +2 more
core +2 more sources
Percutaneous coronary intervention in the elderly: changes in case-mix and periprocedural outcomes in 31758 patients treated between 2000 and 2007 [PDF]
<p>Background: The elderly account for an increasing proportion of the population and have a high prevalence of coronary heart disease. Percutaneous coronary intervention (PCI) is the most common method of revascularization in the elderly.
Eteiba, H. +9 more
core +1 more source
Acute Iatrogenic Agranulocytosis: A Rare and Dire Case of an Adverse Drug Reaction to Be Aware
Background. Iatrogenic agranulocytosis (IA), by nonchemotherapeutic drugs, is a rare adverse event, resulting in a neutrophil count under 0.5 × 109 cells/L with fever or other suggestive signs of infection. Methods.
Diogo André +5 more
doaj +1 more source
Abstract Objectives There are limited reports on the safety of gastrointestinal endoscopic procedures in individuals taking edoxaban, one of the direct oral anticoagulants. We clarified the incidence of delayed bleeding in patients who were on edoxaban in the perioperative period of gastrointestinal endoscopic procedures with a high risk of bleeding ...
Ken‐ichi Mizuno +9 more
wiley +1 more source
S-Nitrosoglutathione reduces asymptomatic embolization after carotid angioplasty [PDF]
Background: The major complication of carotid angioplasty is embolic stroke, which may occur after balloon inflation and deflation or in the early postintervention period.
Clifton, A. +4 more
core +1 more source
Spontaneous splenic haemorrahge and rupture is a rare but life-threatening condition requiring urgent diagnosis and treatment. Splenic haemorrhage and rupture precipitated by thrombolytic or antiocoagulant therapy has been reported frequently in the ...
Garge S Shaileshkumar +4 more
doaj +1 more source

