Effects of tidal volume challenge on the reliability of plethysmography variability index in hepatobiliary and pancreatic surgeries: a prospective interventional study. [PDF]
Abstract The plethysmography variability index (PVI) is a safe, non-invasive, and useful parameter for evaluating fluid responsiveness but it does not reliably predict fluid responsiveness during low tidal volume (VT) ventilation. We hypothesized that in a ‘tidal volume challenge’ with a transient increase in tidal volume from 6 to 8 ml/kg, the
Botros JM +4 more
europepmc +4 more sources
Efficacy of Changes in Pulse Pressure Variation During Tidal Volume Challenge Test to Predict Fluid Responsiveness in Low Tidal Volume Ventilated Critically ill Patients [PDF]
Background: Fluid administration is one of the first-line therapy interventions used to reverse tissue hypoperfusion during acute circulatory failure.
Saied Ali +2 more
doaj +2 more sources
Role of Muscarinic Receptor Signaling Processes in Specific Aspects of Morphine-Induced Respiratory Depression in Rats [PDF]
Background/Objectives: We examined the role of muscarinic cholinergic receptors in the ventilatory depressant effects of morphine in male Sprague Dawley rats, and in responses elicited by a hypoxic-hypercapnic gas (HH) challenge and upon return to room ...
Paulina M. Getsy +7 more
doaj +2 more sources
L-Cysteine Ethyl Ester May Overcome Morphine-Induced Respiratory Depression by Activating Muscarinic Receptors [PDF]
Background/Objectives: Opioids inhibit breathing that can lead to fatal overdose, highlighting the need for testing effective countermeasure agents and potential mechanisms of action. Here we examined the role muscarinic cholinergic receptors play in the
Paulina M. Getsy +9 more
doaj +2 more sources
Detecting if change in end-tidal carbon dioxide signifies change in cardiac output for the prediction of fluid responsiveness in patients undergoing major abdominal oncosurgery: An observational study [PDF]
Background and Aims: Changes in end-tidal carbon dioxide (ΔETCO2) have been proposed as a predictor of fluid responsiveness, but the available evidence remains inconsistent.
Shreyas Arun Chawathey +2 more
doaj +2 more sources
Background and Aims: Tidal volume (TV) challenge was shown to improve the reliability of pulse pressure variation (PPV) in predicting volume responsiveness. Carotid peak velocity (CPV) has similar potential to predict volume responsiveness.
Koteshwar Rao Madhisetti +4 more
doaj +2 more sources
Precision fluid therapy in sepsis: fluid responsiveness vs. fluid tolerance [PDF]
Intravenous fluid is the most frequently administered drug in septic shock and one of the least precisely dosed. Two decades of trials have progressively dismantled the assumption that more fluid is better: protocolized early goal-directed therapy failed
Ali Araghi
doaj +2 more sources
Comparison of Changes in PPV Using a Tidal Volume Challenge with a Passive Leg Raising Test to Predict Fluid Responsiveness in Patients Ventilated Using Low Tidal Volume. [PDF]
Tidal volume challenge pulse pressure variation (TVC-PPV) is considered one of the recent reliable dynamic indices of fluid responsiveness (FR); also, passive leg raising (PLR)-induced changes in cardiac output (CO) detected by echocardiography are considered a reliable reversible self-fluid challenge test; many patients share eligibility for both ...
Elsayed AI +4 more
europepmc +3 more sources
Use of 'tidal volume challenge' to improve the reliability of pulse pressure variation. [PDF]
AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Myatra SN, Monnet X, Teboul JL.
europepmc +3 more sources
Testing preload responsiveness by the tidal volume challenge assessed by the photoplethysmographic perfusion index. [PDF]
To detect preload responsiveness in patients ventilated with a tidal volume (Vt) at 6 mL/kg of predicted body weight (PBW), the Vt-challenge consists in increasing Vt from 6 to 8 mL/kg PBW and measuring the increase in pulse pressure variation (PPV). However, this requires an arterial catheter.
Bruscagnin C +9 more
europepmc +6 more sources

