Tidal Volume Challenge to Assess Volume Responsiveness with Dynamic Preload Indices During Non-Cardiac Surgery: A Prospective Study. [PDF]
Background/Objectives: The aim of this study is to assess whether changes in Pulse Pressure Variation (PPV) and Stroke Volume Variation (SVV) following a VtC can predict the response to fluid administration in patients undergoing surgery under general anesthesia with protective mechanical ventilation.
Griva P +5 more
europepmc +4 more sources
Tidal volume challenge to predict fluid responsiveness in the operating room
Pulse pressure variation (PPV) and stroke volume variation (SVV) do not predict fluid responsiveness when using a protective ventilation strategy: the use of functional haemodynamic tests can be useful to overcome this limitation.We tested the use of a tidal volume challenge (VTC), during 6 ml kg [predicted body weight (PBW)] ventilation, and the end ...
Messina A. +8 more
+7 more sources
Methacholine challenges: comparison of different tidal breathing challenge methods
Tidal-breathing methacholine challenges are now recommended by guidelines, to avoid the bronchoprotective effects of deep inhalation. This study compared different tidal breathing methacholine challenge methods; assessed the agreement between tidal ...
James Dean +4 more
doaj +1 more source
Prediction of fluid responsiveness. What’s new?
Although the administration of fluid is the first treatment considered in almost all cases of circulatory failure, this therapeutic option poses two essential problems: the increase in cardiac output induced by a bolus of fluid is inconstant, and the ...
Xavier Monnet +2 more
doaj +1 more source
How I personalize fluid therapy in septic shock?
During septic shock, fluid therapy is aimed at increasing cardiac output and improving tissue oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has many well-documented deleterious effects.
Xavier Monnet +2 more
doaj +1 more source
Protective mechanical ventilation in patients without or with lung injury [PDF]
The mortality of Acute Respiratory Distress Syndrome (ARDS) is still high from 27 to 45% according to Berlin definition. Even in surgical patients without lung injury, the postoperative pulmonary complications (PPCs) are frequent.
Sutherasan Yuda +3 more
doaj +3 more sources
Challenges encountered in employing a low tidal volume ventilation strategy in patients at risk of ARDS [PDF]
Ventilator strategies that use tidal volumes (TVs) limited to 6 ml/kg IBW (ideal body weight) have been shown to reduce mortality in patients with ARDS (acute respiratory distress syndrome). [1] It is suggested that using these same low tidal volumes in other critically ill patients may reduce the progression to ARDS. [2, 3] An initial audit in the ICU
Fisher, R +3 more
openaire +1 more source
Slow breathing and hypoxic challenge: cardiorespiratory consequences and their central neural substrates. [PDF]
Controlled slow breathing (at 6/min, a rate frequently adopted during yoga practice) can benefit cardiovascular function, including responses to hypoxia.
Hugo D Critchley +6 more
doaj +1 more source
The roles of endothelial nitric oxide synthase (eNOS) in the ventilatory responses during and after a hypercapnic gas challenge (HCC, 5% CO2, 21% O2, 74% N2) were assessed in freely-moving female and male wild-type (WT) C57BL6 mice and eNOS knock-out ...
Paulina M. Getsy +6 more
doaj +1 more source
Tidal Volume Challenge to Reliably Predict Fluid Responsiveness in Critically Ill Patients – An Interim Analysis [PDF]
INTRODUCTION: Fluid administration is the first line of treatment in patients with acute circulatory failure. Although hypovolemia leading to organ dysfunction and death, excessive fluid loading is associated with increased complications, mortality, and length of ICU stay(1).
Kumari A, Singh R, Kumar S.
europepmc +2 more sources

