Results 111 to 120 of about 67,616 (299)
Tight focusing of partially coherent and radiallly polarized vortex beams
, 2013 We investigate the tight focusing properties of partially coherent and radially polarized vortex beams by use of vectorial Debye theory. It is found that the intensity profiles and the degree of coherence in the focal region are strongly dependent on the
Zhu, Jianqian +4 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The scientific community studies tight focusing of radially and azimuthally-polarized vector beams as it is a versatile solution for many applications.
Leslie A. Rusch, Sushanta Kumar Pal
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Autoethnography in Higher Education Research : A Marginal Methodology for the Marginalized?
Autoethnography as a methodology has proved increasingly attractive to higher education researchers in recent years, particularly those in marginalized positions.
Tight, Malcolm
core
, 2013 This chapter discusses the main challenges in higher education comparative research, focusing on cross-national forms of comparison and presenting examples from European research.
Antonucci, Lorenza, Lorenza Antonucci
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Assessing the benefits and risks of tight glycemic control in critically ill children
, 2014 Sarah B Kandil, E Vincent Faustino Department of Pediatrics, Division of Pediatric Critical Care, Yale University School of Medicine, New Haven, CT, USA Abstract: The benefit of intravenous insulin for tight glycemic control (TGC) in critically ill ...
Kandil SB, Faustino EV
core