Results 131 to 140 of about 192,480 (283)

VILO SLAM: Tightly Coupled Binocular Vision-Inertia SLAM Combined with LiDAR. [PDF]

Sensors (Basel), 2023
Peng G, Zhou Y, Hu L, Xiao L, Sun Z, Wu Z, Zhu X.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Zero-Velocity Update-Based GNSS/IMU Tightly Coupled Algorithm with the Constraint of the Earth's Rotation Angular Velocity for Cableway Bracket Deformation Monitoring. [PDF]

Sensors (Basel), 2023
Zhang S, Zhang Q, Yu R, Yu Z, Zhang C, He X.   +5 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Message-Based Agent Communications in a Tightly Coupled Multiagent System

, 1995
vocabularies that are exchanged among agents. Namely, it is possible that the same word means different things (ambiguity), or different words mean the same thing (conflicts) in different agents [5].
Myeong-Wuk Jang, Sang-Kyu Park, Soon-cheol Baeg, Gowang-Lo Lee, Young-hwan Lim, Joongmin Choi   +5 more
core  

A wideband common-mode suppression filter for bend discontinuities in differential signaling using tightly coupled microstrips

, 2010
A new type of bend is proposed that reduces differential-to-common mode conversion occuring at the bend discontinuity in coupled microstrip lines for high-speed digital circuits.
Gazda, Celina, De Zutter, Daniël, Vande Ginste, Dries, Rogier, Hendrik, Daniel De Zutter, Dries Vande Ginste, Ruey-Beei Wu, Wu, Ruey-Beei, Hendrik Rogier, Celina Gazda   +9 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source