Results 201 to 210 of about 139,675 (244)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Genetic polymorphisms of TIM-3 and its association with asthma in familial cluster asthma. [PDF]

Postepy Dermatol Alergol
Maolahong S, Chen JH, Cai XT, Cong L, Chen Y, Lian ZC, Chen LP.   +6 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

TIM-3 blockade reverses oncolytic vaccinia virus-induced DCs inactivation and T cells exhaustion to improve antitumor immunity and therapeutic efficacy. [PDF]

J Exp Clin Cancer Res
Ye P, Wu Y, Yang X, Wu H, Xia Y, Wu G, Cheng G, Sun W, Zhang J, Wang S, Tong X.   +10 more
europepmc   +1 more source

Elevated Serum Soluble Tim-3 in Primary Biliary Cholangitis: Lack of Correlation with Cytokines, Chemokines, and Clinical Parameters. [PDF]

Turk J Gastroenterol
Xu J, Ma H, Dang F, Lin H, Zhang C, Wang Q, Tan X, Yang X, Zhang J, Bao W, Tang Y.   +10 more
europepmc   +1 more source

Evaluation of PD-L1 and TIM-3 Pathways in T Cells During Experimental Bovine Leukemia Virus Infection in Sheep. [PDF]

Vet Sci
Tiyamanee W, Okagawa T, Yamada S, Ikehata M, Nakamura H, Inoue M, Maekawa N, Kato Y, Murata S, Ohashi K, Murakami K, Konnai S.   +11 more
europepmc   +1 more source

T Cell Exhaustion in the Cervical Cancer Tumor Microenvironment: PD-1 Overexpression and Co-Expression with TIGIT, Tim-3, LAG-3, and NKG2A. [PDF]

Cancers (Basel)
García-Barrientos NT, Solorzano-Ibarra F, Klimov-Kravtchenko K, Rojas-Diaz JM, Guitron-Aviña MS, Ceja-Flores FJ, Cruz-Ramos JA, Ortiz-Lazareno PC, Bustos-Rodriguez FJ, Vazquez-Limon JC, Bueno-Topete MR, Tellez-Bañuelos MC, Haramati J, Del Toro-Arreola S.   +13 more
europepmc   +1 more source

Tim-3 pathway dysregulation and targeting in sepsis-induced immunosuppression. [PDF]

Eur J Med Res
Luo J, Zhang C, Chen D, Chang T, Chen S, Lin Z, Yi C, Tang ZH.   +7 more
europepmc   +1 more source

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TIM-3: An update on immunotherapy

International Immunopharmacology, 2021
T cell immunoglobulin and mucin domain 3 (TIM-3) was originally found to be expressed on the surface of Th1 cells, acting as a negative regulator and binding to the ligand galectin-9 to mediate Th1 cell the apoptosis. Recent studies have shown that TIM-3 is also expressed on other immune cells, such as macrophages, dendritic cells, and monocytes.
Lizhen Zhao, Shaoyun Cheng, Lin Fan
exaly   +3 more sources

Importance of photophosphatidylserine and Tim-3 in photoimmunotherapy

RSC Medicinal Chemistry, 2022
Natural killer (NK) cells help regulate autoimmune reactions, but overactivation causes harm.
Akshansh Sharma, Arun Kumar, Sadanand Pandey, Deepak Kumar   +3 more
openaire   +2 more sources