Results 41 to 50 of about 88,713,293 (287)
Immunoregulation effects of TIM-3 on tumors
Neoplasma, 2019 Cancer poses a serious threat to human health and its increasing incidence has made it one of the most common causes of death. Immune factors affect in vivo tumor cell survival and expansion, and cancer patients have obvious cell immune dysfunction and low anti-tumor immunity.
C C, Sheng, F Y, Han
openaire +3 more sources
Establishment of novel anti-TIM-3 antibodies interfering with its binding to ligands
HeliyonThe T cell immunoglobulin and mucin-domain containing-3 (TIM-3) receptor has gained significant attention as a promising target for cancer immunotherapy.
Zhuohong Yan +6 more
doaj +1 more source
Editorial: Tim-3 puts on the brakes [PDF]
Journal of Leukocyte Biology, 2012 Discussion on how Tim-3 negatively regulates both innate and adaptive immune responses.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
Tim-3 expression defines regulatory T cells in human tumors. [PDF]
PLoS ONE, 2013 Tim-3, a member of the novel Tim (T cell immunoglobulin and mucin domain) family, has been reported to negatively regulate the immune responses against viral infection and had implications for autoimmune disease.
Jing Yan +5 more
doaj +1 more source
TIM-3, a potential target for sepsis therapy. [PDF]
Chin J TraumatolImmune dysregulation is one of the leading causes of mortality in patients with sepsis. T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), a negative costimulatory molecule, is pivotal for immune regulation during sepsis. The effects of TIM-3 appear to be bidirectional: in the early stages of sepsis, upregulation of TIM-3 may help ...
Huang S +9 more
europepmc +3 more sources
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source