Results 61 to 70 of about 159,423 (276)
What Do Forbidden Light-ray Fields Look Like? [PDF]
, 2014 Ray-optically, optical components change a light-ray field on a surface immediately in front of the component into a different light-ray field on a surface behind the component.
Courtial, Johannes +3 more
core +1 more source
Lack of TIM-3 Immunoregulation in Multiple Sclerosis [PDF]
The Journal of Immunology, 2008 Abstract Multiple sclerosis (MS) is an inflammatory disease of the CNS white matter associated with T cell infiltrates and alterations of immune functions that can be measured in the peripheral immune system. TIM-3 has been identified as a central regulator of IFN-γ-secreting type 1 Th (Th1) cells and immune tolerance.
Li, Yang +3 more
openaire +2 more sources
Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez +14 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source
Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus [PDF]
Brazilian Journal of Medical and Biological Research, 2015 The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the
X.Z. Cai +9 more
doaj +3 more sources
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
TIM-3 Rs10515746 (A/C) and Rs10053538 (C/A) Gene Polymorphisms and Risk of Multiple Sclerosis
Iranian Journal of Public Health, 2016 Background: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) caused by autoreactive T cells against myelin antigens.
Esmat YAGHOOBI +3 more
doaj
Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection
Veterinary Research, 2012 The immunoinhibitory receptor T cell immunoglobulin domain and mucin domain-3 (Tim-3) and its ligand, galectin-9 (Gal-9), are involved in the immune evasion mechanisms for several pathogens causing chronic infections.
Okagawa Tomohiro +8 more
doaj +1 more source
One Stone, Two Birds: The Roles of Tim-3 in Acute Myeloid Leukemia
Frontiers in Immunology, 2021 T cell immunoglobulin and mucin protein 3 (Tim-3) is an immune checkpoint and plays a vital role in immune responses during acute myeloid leukemia (AML).
Zhiding Wang +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba +11 more
wiley +1 more source