Results 101 to 110 of about 22,475,071 (287)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Robust filtering for a class of stochastic uncertain nonlinear time-delay systems via exponential state estimation [PDF]
, 2001 Copyright [2001] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Wang, Z, Burnham, KJ
core +3 more sources
Delay-Dependent Stability Criterion of Arbitrary Switched Linear Systems with Time-Varying Delay
Discrete Dynamics in Nature and Society, 2010 This paper deals with the problem of delay-dependent stability criterion of arbitrary switched linear systems with time-varying delay. Based on switched quadratic Lyapunov functional approach and free-weighting matrix approach, some linear matrix ...
Jun Li +4 more
doaj +1 more source
IEEE Access, 2019 This paper presents a discrete-time adaptive control approach for nonlinear systems with input delay. The nonlinearity is assumed to be non-sector bounded, resulting in the key technical lemma being inapplicable.
Khalid Abidi, Ian Postlethwaite
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On the Genericity of Stabilizability for Time-Delay Systems [PDF]
SIAM Journal on Control and Optimization, 1996 The stabilizability of linear delay systems of the form \[ \dot x(t)= A(\sigma)x(t)+ B(\sigma)u(t) \] where \[ (\sigma y)(t)= y(t-\tau) \] and \(A(s)\in \mathbb{R}[s]^{n\times n}\), \(B(s)\in \mathbb{R}[s]^{n\times m}\) is shown to be generic in the sense that such systems are open and dense in the space \[ V=\{(A(s),B(s),\tau): A(s)\in \mathbb{R}[s ...
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
, 2009 We have analyzed the identifiability of time-lag parameters in nonlinear delay systems using an algebraic framework. The identifiability is determined by the form of the system's input-output representation.
Wennberg, Bernt +5 more
core +1 more source
Delay-Dependent H∞ Control for Descriptor Markovian Jump Systems with Time-Varying Delay
Journal of Applied Mathematics, 2013 This paper is concerned with the delay-dependent H∞ control problem for continuous-time descriptor Markovian jump systems with time-varying delay. By constructing various Lyapunov-Krasovskii functionals for different subsystems, together with delay ...
Jinghao Li +3 more
doaj +1 more source