Results 81 to 90 of about 1,659,892 (314)

When classical nonlinear time-delay state-space systems admit an input-output equation of neutral type

open access: yes, 2010
This paper deals with nonlinear retarded time-delay systems that surprisingly admit an input-output representation of neutral type. It is shown that such an unexpected behaviour represents a strictly nonlinear phenomenon, for it cannot happen in the ...
Halas, Miroslav   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Stability Analysis of Linear Time-Varying Delay Systems via a Novel Augmented Variable Approach

open access: yesMathematics
This paper investigates the stability issues of time-varying delay systems. Firstly, a novel augmented Lyapunov functional is constructed for a class of bounded time-varying delays by introducing new double integral terms.
Wenqi Liao, Hongbing Zeng, Huichao Lin
doaj   +1 more source

Controllability Analysis of Linear Discrete Time Systems with Time Delay in State

open access: yesAbstract and Applied Analysis, 2012
The controllability issues for linear discrete-time systems with delay in state are addressed. By introducing a new concept, the minimum controllability realization index (MinCRI), the characteristic of controllability is revealed.
Hong Shi, Guangming Xie, Wenguang Luo
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On bounded control of a class of reedforward nonlinear time-delay systems

open access: yes, 2018
For the global stabilization of a family of feedforward nonlinear time-delay systems with linearized identical oscillators, a saturated feedback control is established based on a special canonical form for the considered system. The proposed control laws
Zhou, B, Lam, J, Yang, X
core   +1 more source

Oscillations in First-Order, Continuous-Time Systems via Time-Delay Feedback

open access: yesComplexity, 2018
A technique to generate (periodic or nonperiodic) oscillations systematically in first-order, continuous-time systems via a nonlinear function of the state, delayed by a certain time d, is proposed.
Abimael Salcedo, Joaquin Alvarez
doaj   +1 more source

Synchronization in systems with multiple time delays [PDF]

open access: yesPhysical Review E, 2004
We report on chaos synchronization between two unidirectionally coupled chaotic systems with multiple time delays and find both the existence and stability conditions for anticipating, lag, inverse and complete synchronizations. The method is tested on the famous Ikeda model. Numerical simulations fully support the analytical approach.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Robust H∞ filtering for discrete nonlinear stochastic systems with time-varying delay

open access: yes, 2008
This is the postprint version of the article. The official published version can be accessed from the link below - © 2007 Elsevier IncIn this paper, we are concerned with the robust H∞ filtering problem for a class of nonlinear discrete time-delay ...
Liu, Y   +8 more
core   +1 more source

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