Results 71 to 80 of about 445,678 (263)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Robust Stabilization of Linear Time-Delay Systems under Denial-of-Service Attacks. [PDF]

Sensors (Basel), 2023
Saif AA, El-Ferik S, Elkhider SM.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Weighted Time-Delay Estimation-Based Proportional-Integral-Derivative Control for High-Order Time-Delay Nonlinear Systems

IEEE Access
In real-world applications, time delays and uncertain nonlinearities are inevitable and impose significant challenges in modern control systems. The uncertainties commonly include nonlinear backlash-like hysteresis, external disturbances, parameter ...
Syeda Nadiah Fatima Nahri, Shengzhi Du, Barend J. Van Wyk, Oluwaseun Kayode Ajayi, Tawanda Denzel Nyasulu, Hui Yu   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Generic generation of noise-driven chaos in stochastic time delay systems: Bridging the gap with high-end simulations. [PDF]

Sci Adv, 2022
Chekroun MD, Koren I, Liu H, Liu H.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Ψ-Stability of Nonlinear Volterra Integro-Differential Systems with Time Delay

Abstract and Applied Analysis, 2013
We give some sufficient conditions for Ψ-uniform stability of the trivial solutions of a nonlinear differential system and of nonlinear Volterra integro-differential systems with time delay.
Lianzhong Li, Maoan Han, Xin Xue, Yuanyuan Liu   +3 more
doaj   +1 more source

Delay-dependent stabilization of a class of time-delay nonlinear systems: LMI approach

Advances in Difference Equations, 2017
This paper deals with the state and output feedback stabilization problems for a family of nonlinear time-delay systems satisfying some relaxed triangular-type condition.
Nadhem Echi, Amel Benabdallah
doaj   +1 more source

An alternative design approach for Fractional Order Internal Model Controllers for time delay systems. [PDF]

J Adv Res, 2021
Muresan CI, Birs I, De Keyser R.
europepmc   +1 more source