Results 51 to 60 of about 381,914 (292)

All-cause and cause-specific mortality associated with diabetes in prevalent hemodialysis patients

open access: yesBMC Nephrology, 2012
Background Diabetes is the most common risk factor for end-stage renal disease (ESRD) and has been associated with increased risk of death. In order to better understand the influence of diabetes on outcomes in hemodialysis, we examine the risk of death ...
Sattar Abdus   +6 more
doaj   +1 more source

Survival Impact After Resection for Postoperative Recurrence or Metastasis of Pancreatic Ductal Adenocarcinoma Analyzed Using a Time‐Dependent Cox Regression Model [PDF]

open access: bronzeJournal of Hepato-Biliary-Pancreatic Sciences
ABSTRACT Background Recently, surgical resection has been attempted for postoperative recurrence of pancreatic ductal adenocarcinoma ( PDAC ). This multicenter study aimed to investigate whether resection of any recurrent lesion
Denys Tsybulskyi   +28 more
openalex   +3 more sources

Serum Alkaline Phosphatase Levels are Not Associated with Increased Death Risk in Prevalent Hemodialysis Patients: 5-Year Experience in a Single Hemodialysis Center

open access: yesKidney & Blood Pressure Research, 2016
Background/Aims: Although high serum alkaline phosphatase (ALP) levels were reported as predictive factors for death risk in dialysis patients on the basis of large databank analyses, the real scenario in a single hemodialysis (HD) center is unknown ...
Jin-Gang Zhu   +6 more
doaj   +1 more source

Bias of Maximum-Likelihood estimates in logistic and Cox regression models: A comparative simulation study [PDF]

open access: yes, 2003
Parameter estimates of logistic and Cox regression models are biased for finite samples. In a simulation study we investigated for both models the behaviour of the bias in relation to sample size and further parameters.
Bender, R.   +4 more
core   +2 more sources

Cox regression survival analysis with compositional covariates: application to modelling mortality risk from 24-h physical activity patterns [PDF]

open access: yes, 2020
Survival analysis is commonly conducted in medical and public health research to assess the association of an exposure or intervention with a hard end outcome such as mortality. The Cox (proportional hazards) regression model is probably the most popular
Chastin, S.F.M.   +4 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma. [PDF]

open access: yes, 2019
The MYC oncogene is dysregulated in approximately 30% of liver cancer. In an effort to exploit MYC as a therapeutic target, including in hepatocellular carcinoma (HCC), strategies have been developed on the basis of MYC amplification or gene ...
Bodzin, Adam S.   +9 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The association between inflammation biomarkers with mental and behavioral disorders due to use of tobacco: a cross-section and cohort study

open access: yesBMC Psychiatry
Background Tobacco use was as an unhealthy lifestyle. But there were few studies about mental and behavioral disorders due to use of tobacco (MBDT). Inflammation played a role in several mental and behavioral disorders.
Xinyu Zhang   +5 more
doaj   +1 more source

Impact of fine particulate matter on latent tuberculosis infection and active tuberculosis in older adults: a population-based multicentre cohort study

open access: yesEmerging Microbes and Infections
Evidence showed that air pollution was associated with an increased risk of tuberculosis (TB). This study aimed to study the impact of long-term exposure to ambient particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5) on the ...
Tonglei Guo   +19 more
doaj   +1 more source

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