Results 71 to 80 of about 381,914 (292)

Value of 18F-FDG PET/CT metabolic parameters in predicting the prognosis of patients with oligometastatic colorectal cancer after radical treatment [PDF]

open access: yes精准医学杂志
Objective To investigate the value of 18F-FDG PET/CT metabolic parameters in predicting the prognosis of patients with oligometastatic colorectal cancer (CRC) after radical treatment.
ZHU Zhenhua, ZHAO Xia, LI Bingying, LI Haiwen, SUN Hukui
doaj   +1 more source

Nonparametric inference of doubly stochastic Poisson process data via the kernel method

open access: yes, 2011
Doubly stochastic Poisson processes, also known as the Cox processes, frequently occur in various scientific fields. In this article, motivated primarily by analyzing Cox process data in biophysics, we propose a nonparametric kernel-based inference ...
Kou, S. C., Zhang, Tingting
core   +1 more source

Estimates of influenza vaccine effectiveness in primary care in Scotland vary with clinical or laboratory endpoint and method : experience across the 2010/11 season [PDF]

open access: yes, 2013
Aim: This study examines estimation of seasonal influenza vaccine effectiveness (VE) for a cohort of patients attending general practice in Scotland in 2010/11.
Kavanagh, Kimberley   +2 more
core   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Using flexible methods to determine risk factors for ventilator-associated pneumonia in the Netherlands.

open access: yesPLoS ONE, 2019
Seven hospitals participated in the Dutch national surveillance for ventilator-associated pneumonia (VAP) and its risk factors. We analysed time-independent and time-dependent risk factors for VAP using the standard Cox regression and the flexible ...
Tjallie I I van der Kooi   +6 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Enhancing Survival Analysis Model Selection through XAI(t) in Healthcare

open access: yesApplied Sciences
Artificial intelligence algorithms have become extensively utilized in survival analysis for high-dimensional, multi-source data. However, due to their complexity, these methods often yield poorly interpretable outcomes, posing challenges in the analysis
Francesco Berloco   +10 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Prognostic value of plasma diquat concentration in patients with acute oral diquat poisoning: a retrospective study

open access: yesFrontiers in Public Health
ObjectivesDiquat poisoning is an important public health and social security agency. This study aimed to develop a prognostic model and evaluate the prognostic value of plasma diquat concentration in patients with acute oral diquat poisoning, focusing on
Na Meng   +9 more
doaj   +1 more source

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