Results 101 to 110 of about 42,446 (256)

Affinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in Plants

Advanced Science, EarlyView.
ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter, Verena Gaugler, Sara Christina Stolze, Riya Ghosh, Akhila Jayamon, Ranjana Yadav, Felix Wollensack, Debabrata Laha, Hirofumi Nakagami, Gabriel Schaaf, Henning Jacob Jessen   +10 more
wiley   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Radar Waveform Recognition With ConvNeXt and Focal Loss

IEEE Access
A method of automatic recognition of radar waves based on time-frequency analysis (TFA) and ConvNeXt model is proposed in the paper. The method aims to address the challenges of feature extraction difficulty and low recognition correctness in complex ...
Liping Luo, Jie Huang, Yang Yang, Dexiu Hu   +3 more
doaj   +1 more source

Time-frequency component analysis of somatosensory evoked potentials in rats

BioMedical Engineering OnLine, 2009
Background Somatosensory evoked potential (SEP) signal usually contains a set of detailed temporal components measured and identified in a time domain, giving meaningful information on physiological mechanisms of the nervous system.
Luk Keith, Chan Shing-Chow, Yang Jun-Lin, Zhang Zhi-Guo, Hu Yong   +4 more
doaj   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Recent Advances in Zirconium‐Based Metal–Organic Framework Membranes for Desalination

Advanced Science, EarlyView.
Zirconium‐based metal–organic framework membranes with tunable pore architectures, defect chemistry, and surface functionalities for Desalination are systematically reviewed. Their fabrication strategies, desalination performance across pressure‐driven, forward osmosis, and pervaporation processes, and structure–property–performance relationships are ...
Mao Fu, Hai‐Tian Xia, You Wu, Sen Li, Ying Liu, Ya‐Li Liu, Shi‐Qiang Wang, Yingchao Dong   +7 more
wiley   +1 more source

Deep MMT Transit Survey of the Open Cluster M37 IV: Limit on the Fraction of Stars With Planets as Small as 0.3 R_J

, 2008
We present the results of a deep (15 ~< r ~< 23), 20 night survey for transiting planets in the intermediate age open cluster M37 (NGC 2099) using the Megacam wide-field mosaic CCD camera on the 6.5m MMT. We do not detect any transiting planets among the
Alard, Alonso, An, B. A. McLeod, B. S. Gaudi, Bakos, Beatty, Burke, Butler, Butler, Carraro, Endl, Fischer, Fischer, Fortney, Gaudi, Gaudi, Gilliland, Gould, Gratton, Hartman, Hartman, Hartman, Hartman, Ibata, Ida, Ida, J. A. Barranco, J. D. Hartman, J. S. Kalirai, Joachims, Joachims, K. Z. Stanek, Kalirai, Kalirai, Kaluzny, Konacki, Kurucz, M. H. Pinsonneault, M. J. Holman, Mandel, McCullough, McLeod, Mochejska, Mochejska, Origlia, Pepper, Pepper, Press, Rivera, S. Meibom, Skrutskie, Stetson, Szentgyorgyi, Tingley, Torres, Udalski, Vapnik, Vogt, Weldrake, Weldrake   +60 more
core   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

HAT-P-47b AND HAT-P-48b: Two Low Density Sub-Saturn-Mass Transiting Planets on the Edge of the Period--Mass Desert [PDF]

, 2016
We report the discovery of two new transiting extrasolar planets orbiting moderately bright (V = 10.7 and 12.2 mag) F stars (masses of 1.39 Msun and 1.10 Msun, respectively).
Bakos, G. Á., Bieryla, A., Buchhave, L. A., Béky, B., Csubry, Z., Esquerdo, G. A., Everett, M., Fulton, B. J., Hartman, J. D., Howard, A. W., Kovács, G., Kovács, T., Latham, D. W., Lázár, J., Marcy, G. W., Noyes, R. W., Papp, I., Penev, K., Quinn, S. N., Sato, B., Shporer, A., Szklenár, T., Sári, P., Torres, G.   +23 more
core   +1 more source