Results 111 to 120 of about 124,888,785 (314)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Time to arrival by mode of arrival.
Time to arrival by mode of arrival.
Hannah Janeway (7037423) +4 more
core +1 more source
Constrained Weighted Least-Squares Algorithms for 3-D AOA-Based Hybrid Localization
Source localization with time-of-arrival (TOA), time-difference-of-arrival (TDOA), time-delay (TD), received-signal-strength (RSS), or angle-of-arrival (AOA) measurements from several spatially distributed sensors is commonly used in practice.
Yanbin Zou +3 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
`Inter-Arrival Time' Inspired Algorithm and its Application in Clustering and Molecular Phylogeny
Inter-Arrival Time' Inspired Algorithm and its Application in Clustering and Molecular Phylogeny This study involves the proposition of alignment-free distance measure for sequence analysis with its application in clustering and molecular phylogeny, as a
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Listening to Young People’s Perspectives on Out-of-School Time Opportunities [PDF]
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Youth Voices focus groups were conducted with 101 middle ...
Saito, Rebecca +1 more
core
Research of Batch Scheduling with Arrival Time Based on Estimation of Distribution Algorithm
Estimation of distribution has been used to solve the batch scheduling problem with job release problem, which minimizing the make span as the objective function.
Xiaofeng Zhou +7 more
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

