Results 91 to 100 of about 166,620,327 (286)

Constrained Weighted Least-Squares Algorithms for 3-D AOA-Based Hybrid Localization

IEEE Open Journal of Signal Processing
Source localization with time-of-arrival (TOA), time-difference-of-arrival (TDOA), time-delay (TD), received-signal-strength (RSS), or angle-of-arrival (AOA) measurements from several spatially distributed sensors is commonly used in practice.
Yanbin Zou, Wenbo Wu, Jingna Fan, Huaping Liu   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Variants of the Arrival problem [PDF]

Arrival is a decision problem with, as yet, neither a known polynomial time algorithm nor a P-hardness result. The natural witness-search problem for Arrival also lies in many interesting sub-classes of TFNP. In this thesis, we will explore further the
Webster, Thomas
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Two Stages of Arrival Aircraft: Influencing Factors and Prediction of Integrated Arrival Time

Aerospace
To enhance the accuracy and real-time capability of estimated in-block time (EIBT) predictions at airports, this study proposes a two-stage integrated prediction method.
Xiaowei Tang, Mengfan Ye, Jiaqi Wu, Shengrun Zhang   +3 more
doaj   +1 more source

Underground positioning method of single base station DOA and TOA based on single reflectio

Gong-kuang zidonghua, 2015
In view of problem of big error in underground single base station positioning system due to wireless signal influenced by multipath effect and non-line of sight, a joint estimation positioning method of DOA and TOA based on single reflection was ...
HUANG Kai, ZHAI Yanrong, ZHANG Pengcheng, ZHU Mengying   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Phase Difference of Arrival Aided Downlink Time Difference of Arrival Ultra-Wide Band Positioning System

IEEE Access
Currently there is a growing demand for accurate and reliable positioning indoors or in other environments, where Global Navigation Satellite Systems (GNSS) are unavailable.
Josef Krska, Christian Gentner, Vaclav Navratil   +2 more
doaj   +1 more source