Results 81 to 90 of about 166,620,327 (286)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

MEASUREMENTS OF ARRIVAL TIME DISTRIBUTIONS OF EAS MUONS WITH THE FACILITIES OF THE KASCADE CENTRAL DETECTOR

open access: yes, 2007
The central detector of the KASCADE experiment is equipped with a trigger and timing facility, which enables measurements of the arrival time distributions of muons hitting the central detector.
M. Foller   +2 more
core  

Cooperative localization algorithm based on time-ofarrival in wireless senor network

open access: yesDianxin kexue, 2019
A novel cooperative location method based on time-of-arrival in wireless senor networks was proposed. Firstly, the optimization problem for the target location was established.
Qianqian LU   +3 more
doaj  

Performance Analysis of the Anchor-free Localization Algorithm with Low-Complexity Method for Node Distance Estimation Enhancement Using ToA [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2013
The Ultra Wide-Band (UWB) communication technology is used in ToA and these systems are capable resolving individual multipath components in the received Channel Impulse Response and determining their time of their arrival very precisely. In this article
CIPOV Vladimír   +2 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Integrating Twitter Traffic Information with Kalman Filter Models for Public Transportation Vehicle Arrival Time Prediction

open access: yes, 2015
Accurate bus arrival time prediction is key for improving the attractiveness of public transport, as it helps users better manage their travel schedule.
Hussain, Amir   +5 more
core   +1 more source

Relativistic Time of Arrival

open access: yes, 1999
We propose a covariant algorithm for relativistic ideal measurements and for relativistic continuous measurements, its non-relativistic limit results the algorithm of the Event-Enhanced Quantum Theory. Therefore an additional intrinsic parameter, the proper time, is used.
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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