Analysis of liposome model systems by time-of-flight secondary ion mass spectrometry. [PDF]
Time‐of‐flight secondary ion mass spectrometry (ToF‐SIMS) is an important technique for studying chemical composition of micrometer scale objects because of its high spatial resolution imaging capabilities and chemical specificity.
Lovrić J +6 more
europepmc +6 more sources
Direct visualization of chemical transport in solid-state chemical reactions by time-of-flight secondary ion mass spectrometry [PDF]
Systematic control and design of solid-state chemical reactions is required for modifying materials properties and in novel synthesis. Understanding chemical dynamics at the nanoscale is therefore essential to reveal the key reactive pathways. Herein, we
Pham Sang, Collins Sean
doaj +4 more sources
Time-of-flight secondary ion mass spectrometry in the helium ion microscope
A helium ion microscope, known for high resolution imaging and modification with helium or neon ions, has been equipped with a time-of-flight spectrometer for compositional analysis. Here we report on its design, implementation and show first results of this powerful add-on.
Klingner, N. +4 more
openaire +5 more sources
Detection of ZrO2 Nanoparticles in Lung Tissue Sections by Time-of-Flight Secondary Ion Mass Spectrometry and Ion Beam Microscopy [PDF]
The increasing use of nanoparticles (NP) in commercial products requires elaborated techniques to detect NP in the tissue of exposed organisms. However, due to the low amount of material, the detection and exact localization of NP within tissue sections ...
Lothar Veith +8 more
doaj +2 more sources
Microscope imaging by time-of-flight secondary ion mass spectrometry [PDF]
The concept of Secondary Ion Microscopy, introduced by Castaing et al. [1], is applied to a direct imaging time-of-flight (TOF) mass spectrometer. The ion optical configuration for a particular [2] stigmatic imaging TOF mass spectrometer is reviewed. A number of fundamental factors influencing the mass resolution in any TOF spectrometer are discussed ...
Bruno W. Schueler
openaire +2 more sources
Human striated muscle samples, from male control and Duchenne muscular dystrophy-affected children, were subjected to cluster-time-of-flight secondary ion mass spectrometry (cluster-ToF-SIMS) imaging using a 25 keV Bi3+ liquid metal ion gun under static ...
Nora Tahallah +3 more
doaj +3 more sources
Biological tissue imaging with time‐of‐flight secondary ion mass spectrometry and cluster ion sources [PDF]
AbstractTime‐of‐flight secondary ion mass spectrometry (TOF‐SIMS) using liquid metal ion guns (LMIGs) is now sensitive enough to produce molecular‐ion images directly from biological tissue samples. Primary cluster ions strike a spot on the sample to produce a mass spectrum. An image of this sample is achieved by rastering the irradiated point over the
Brunelle, Alain +2 more
openaire +4 more sources
Electrospray propulsion time-of-flight secondary ion mass spectrometry diagnostic
The design and capability of a novel electrospray propulsion time-of-flight secondary ion mass spectrometry (TOF-SIMS) diagnostic are presented to investigate secondary species emission from surface impingement of energetic molecular ion plumes. Designed on the basis of traditional SIMS principles, this diagnostic provides information on the relative ...
Giuliana C. Hofheins +2 more
openaire +5 more sources
Imaging and quantitative analysis of insecticide in mosquito net fibers using Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS). [PDF]
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) analysis was used to qualitatively and quantitatively assess the distribution of permethrin insecticide on the surfaces and interiors of Olyset long-lasting insecticidal net (LLIN) fibers.
Stephen C Smith +3 more
doaj +2 more sources
ATP-Mediated Compositional Change in Peripheral Myelin Membranes: A Comparative Raman Spectroscopy and Time-Of-Flight Secondary Ion Mass Spectrometry Study. [PDF]
In the present paper we addressed a mechanism of the myelin reorganization initiated by extracellular ATP and adenosine in sciatic nerves of the frog Rana temporaria.
Nikolay Kutuzov +4 more
doaj +2 more sources

