Results 101 to 110 of about 424,486 (315)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Analysis of thermoelastic laminated Timoshenko beam with time-varying delay

Partial Differential Equations in Applied Mathematics
This document presents a study into a linear thermoelastic laminated Timoshenko beam featuring a time-varying delay. Utilizing the semigroup method and the variable norm technique, we establish the well-posedness of the system.
Besma Founas, Fares Yazid, Fatima Siham Djeradi, Djamel Ouchenane, Erhan Pişkin, Salah Boulaaras   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

New Absolute Stability Conditions of Lur’e Systems with Time-Varying Delay

Journal of Control Science and Engineering, 2015
This paper is focused on the absolute stability of Lur’e systems with time-varying delay. Based on the quadratic separation framework, a complete delay-decomposing Lyapunov-Krasovskii functional is constructed. By considering the relationship between the
Wei Wang, Hong-Bing Zeng
doaj   +1 more source

Active fault-tolerant control for switched systems with time delay

, 2011
Link to a related website: http://vuir.vu.edu.au/7209/1/ACSP-09-0185.pdf, Open Access via UnpaywallThis paper focuses on the problem of active fault-tolerant control for switched systems with time delay.
Shi, Peng, Du, Dongsheng, Du, D., Peng Shi, Jiang, Bin, Dongsheng Du, Bin Jiang, Jiang, B., Shi, P.   +8 more
core   +1 more source

Positivity of Continuous-Time Descriptor Systems With Time Delays [PDF]

, 2014
This technical note is concerned with positivity characteristic of continuous-time descriptor systems with time delays. First, a set of necessary and sufficient conditions is presented to check the property.
Yan, Xinggang, Zhang, Youmei, Tanaka, Tamaki, Zhang, Qingling   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

H∞ filtering for uncertain stochastic time-delay systems with sector-bounded nonlinearities

, 2008
This is the post print version of the article. The official published version can be obtained from the link - Copyright 2008 Elsevier Ltd.In this paper, we deal with the robust H∞ filtering problem for a class of uncertain nonlinear time-delay stochastic
Liu, Y, Liu, X, Wang, Z, Liu, Xiaohui., Wang, Zidong., Yurong Liu (9814022), Z Wang (81545), X Liu (7756691), Liu, Yurong.   +8 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Delay-Dependent Robust Exponential Stability for Uncertain Neutral Stochastic Systems with Interval Time-Varying Delay

Journal of Applied Mathematics, 2012
This paper discusses the mean-square exponential stability of uncertain neutral linear stochastic systems with interval time-varying delays. A new augmented Lyapunov-Krasovskii functional (LKF) has been constructed to derive improved delay-dependent ...
Weihua Mao, Feiqi Deng, Anhua Wan
doaj   +1 more source