Results 91 to 100 of about 15,896,748 (297)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Active fault-tolerant control for switched systems with time delay [PDF]

, 2011
Link to a related website: http://vuir.vu.edu.au/7209/1/ACSP-09-0185.pdf, Open Access via UnpaywallThis paper focuses on the problem of active fault-tolerant control for switched systems with time delay.
Shi, Peng, Du, Dongsheng, Du, D., Peng Shi, Jiang, Bin, Dongsheng Du, Bin Jiang, Jiang, B., Shi, P.   +8 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Stability analysis of discrete‐time systems with a time‐varying delay via improved methods

IET Control Theory & Applications
This paper is concerned with the stability analysis of discrete‐time systems with a time‐varying delay. The conservatism and computation burden are two important factors to evaluate a stability condition.
Hongjia Sha, Ju H. Park, Jun Chen, Mingbo Zhu, Chengjie Nan   +4 more
doaj   +1 more source

Robust Exponential Stability for LPD Discrete-Time System with Interval Time-Varying Delay

Journal of Applied Mathematics, 2012
This paper investigates the problem of robust exponential stability for uncertain linear-parameter dependent (LPD) discrete-time system with delay. The delay is of an interval type, which means that both lower and upper bounds for the time-varying delay ...
Kanit Mukdasai
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

H∞ filtering for uncertain stochastic time-delay systems with sector-bounded nonlinearities [PDF]

, 2008
This is the post print version of the article. The official published version can be obtained from the link - Copyright 2008 Elsevier Ltd.In this paper, we deal with the robust H∞ filtering problem for a class of uncertain nonlinear time-delay stochastic
Liu, Y, Liu, X, Wang, Z, Liu, Xiaohui., Wang, Zidong., Yurong Liu (9814022), Z Wang (81545), X Liu (7756691), Liu, Yurong.   +8 more
core   +1 more source

Stabilization of linear continuous time-varying systems with state delays in Hilbert spaces

Electronic Journal of Differential Equations, 2001
This paper studies the stabilization of the infinite-dimensional linear time-varying system with state delays $$dot x = A(t)x + A_1(t)x(t-h)+B(t)u,.$$ The operator $A(t)$ is assumed to be the generator of a strong evolution operator.
Vu Ngoc Phat
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source