Results 71 to 80 of about 248,754 (265)

Stability analysis of discrete‐time systems with a time‐varying delay via improved methods

IET Control Theory & Applications
This paper is concerned with the stability analysis of discrete‐time systems with a time‐varying delay. The conservatism and computation burden are two important factors to evaluate a stability condition.
Hongjia Sha, Ju H. Park, Jun Chen, Mingbo Zhu, Chengjie Nan   +4 more
doaj   +1 more source

Robust Exponential Stability for LPD Discrete-Time System with Interval Time-Varying Delay

Journal of Applied Mathematics, 2012
This paper investigates the problem of robust exponential stability for uncertain linear-parameter dependent (LPD) discrete-time system with delay. The delay is of an interval type, which means that both lower and upper bounds for the time-varying delay ...
Kanit Mukdasai
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Stabilization of linear continuous time-varying systems with state delays in Hilbert spaces

Electronic Journal of Differential Equations, 2001
This paper studies the stabilization of the infinite-dimensional linear time-varying system with state delays $$dot x = A(t)x + A_1(t)x(t-h)+B(t)u,.$$ The operator $A(t)$ is assumed to be the generator of a strong evolution operator.
Vu Ngoc Phat
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Analysis of thermoelastic laminated Timoshenko beam with time-varying delay

Partial Differential Equations in Applied Mathematics
This document presents a study into a linear thermoelastic laminated Timoshenko beam featuring a time-varying delay. Utilizing the semigroup method and the variable norm technique, we establish the well-posedness of the system.
Besma Founas, Fares Yazid, Fatima Siham Djeradi, Djamel Ouchenane, Erhan Pişkin, Salah Boulaaras   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

New Absolute Stability Conditions of Lur’e Systems with Time-Varying Delay

Journal of Control Science and Engineering, 2015
This paper is focused on the absolute stability of Lur’e systems with time-varying delay. Based on the quadratic separation framework, a complete delay-decomposing Lyapunov-Krasovskii functional is constructed. By considering the relationship between the
Wei Wang, Hong-Bing Zeng
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source