Results 101 to 110 of about 4,649,254 (341)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

New related-key rectangle attack on 42-round SHACAL-2

Tongxin xuebao, 2009
A new 34-round related-key rectangle distinguisher was constructed by exploiting the properties of the round transform of SHACAL-2. Moreover, two new relate-key rectangle attacks on 40-round and 42-round reduced SHACAL-2 were presented by using both the ...
WEI Yong-zhuang1, 2
doaj  

Center of Trapezoid Graph: Application in Selecting Center Location to Set up a Private Hospital

Mathematics
The central location problem is a key aspect of graph theory, with a significant importance in various applications and studies within the field. The center of a graph is made up of nodes that have the smallest eccentricity, where eccentricity is defined
Shaoli Nandi, Sukumar Mondal, Sovan Samanta, Sambhu Charan Barman, Leo Mrsic, Antonios Kalampakas   +5 more
doaj   +1 more source

Efficient and Accurate Hausdorff Distance Computation Based on Diffusion Search

IEEE Access, 2018
The Hausdorff distance (HD) between two point sets is widely used in similarity measures, but the high computational cost of HD algorithms restrict their practical use.
Dejun Zhang, Lu Zou, Yilin Chen, Fazhi He   +3 more
doaj   +1 more source

Improving the smoothed complexity of FLIP for max cut problems

, 2018
Finding locally optimal solutions for max-cut and max-$k$-cut are well-known PLS-complete problems. An instinctive approach to finding such a locally optimum solution is the FLIP method. Even though FLIP requires exponential time in worst-case instances,
Bibak, Ali, Carlson, Charles, Chandrasekaran, Karthekeyan   +2 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reconstruction of Optical Coherence Tomography Images from Wavelength Space Using Deep Learning

Sensors
Conventional Fourier domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into a wavenumber (k) domain to extract the depth profile.
Maryam Viqar, Erdem Sahin, Elena Stoykova, Violeta Madjarova   +3 more
doaj   +1 more source

Optimisation of mobile intelligent terminal data pre-processing methods for crowd sensing

CAAI Transactions on Intelligence Technology, 2018
Sensor data pre-processing is an essential phase of crowd sensing application. Existing studies do not effectively solve the problem, and there still exist various sensor data pre-processing optimisation problems at the acquisition end in crowd-sensing ...
Min Huang, Yuefan Zeng, Lina Chen, Bo Sun   +3 more
doaj   +1 more source

Linear time complexity de novo long read genome assembly with GoldRush. [PDF]

Nat Commun, 2023
Wong J, Coombe L, Nikolić V, Zhang E, Nip KM, Sidhu P, Warren RL, Birol I.   +7 more
europepmc   +1 more source

Stochastic Time Complexity Surfaces of Computing Node [PDF]

, 2023
Α. V. Borisov, Alexey V. Ivanov
openalex   +1 more source