Results 121 to 130 of about 4,649,254 (341)
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
The following remarks are intended as philosophical comments on Gilles Deleuze’s groundbreaking reflections on a control society emerging at the end of the 20th century (cf. Deleuze 1992). Following Foucault, Deleuze’s interpretations of the ‘contemporary’ socio-technological transformations are mostly of a spatio-technical nature; the aim of this ...
Avanessian, Armen, Hennig, Anke
openaire +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Efficient Algorithms for Subgraph Listing
Subgraph isomorphism is a fundamental problem in graph theory. In this paper we focus on listing subgraphs isomorphic to a given pattern graph. First, we look at the algorithm due to Chiba and Nishizeki for listing complete subgraphs of fixed size, and ...
Niklas Zechner, Andrzej Lingas
doaj +1 more source
Low-Complexity Acoustic Scene Classification Using Time Frequency Separable Convolution [PDF]
Duc H. Phan, Douglas L. Jones
openalex +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Enhanced virtual release advancing algorithm for real-time task scheduling
In real-time task scheduling, response time and time complexity are two of important requirements that draw many attentions. Virtual release advancing (VRA) [Tanaka, K. (2015, June). Virtual release advancing for earlier deadlines.
D. Duy, K. Tanaka
doaj +1 more source
The impact of multiple memory formation on dendritic complexity in the hippocampus and anterior cingulate cortex assessed at recent and remote time points [PDF]
Brianne C. Wartman, Matthew R. Holahan
openalex +1 more source
Optimizing Time Complexity of Searching Operation: A Noble Algorithm
Divyanshu Tiwari
openalex +1 more source

