Results 91 to 100 of about 891,103 (297)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Normal Inverse Gaussian Approximation for Arrival Time Difference in Flow-Induced Molecular Communications [PDF]
, 2018 In this paper, we consider molecular communications in one-dimensional flow-induced diffusion channels with a perfectly absorbing receiver. In such channels, the random propagation delay until the molecules are absorbed follows an inverse Gaussian (IG ...
Efrosinin, Dmitry +2 more
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Joint time difference of arrival/angle of arrival position finding in passive radar
IET Radar, Sonar & Navigation, 2009 Several target position finding methods are proposed in various papers mainly regarding sensor networks. However, the problem of position finding in passive radar systems is somewhat different from the general case of sensor networks. Generally, in a passive radar system, there are few receivers located at short distances when compared with the it ...
Y. Norouzi, M. Derakhshani
openaire +1 more source
, 2018 The Laser Interferometer Gravitational-Wave Observatory (LIGO) has recently discovered gravitational waves (GWs) from its first neutron star-neutron star merger at a distance of $\sim 40$~Mpc from the Earth.
Murase, Kohta, Shoemaker, Ian M.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
On the spontaneous breaking of Lorentz invariance
, 2000 We show that estimates of the Lorentz symmetry violation extracted from ultra-high energy cosmic rays beyond the GZK cut-off set bounds on the parameters of a Lorentz-violating extension of the Standard Model.
Amelino-Camelia +47 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Remote SensingThe time difference of arrival (TDOA) estimation plays a crucial role in emitter localization and time synchronization applications. When time among multiple sensors is synchronized, the TDOAs between the sensors and the emitter can be measured to ...
Shanhe Wang +5 more
doaj +1 more source