Results 111 to 120 of about 5,380,901 (293)

A Wear Debris Signal Processing Method Based on Inductive Monitoring for Aero-Engine

Applied Sciences
In view of the high false alarm rate in the oil debris monitoring results of the triple-coil inductive sensor in the transmission lubrication system of the aero-engine, a new debris signal processing method based on inductive monitoring is proposed.
Heng Jiang, Hongfu Zuo, Zhirong Zhong, Jiachen Guo   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Analysis of a space--time hybridizable discontinuous Galerkin method for the advection--diffusion problem on time-dependent domains

, 2018
This paper presents the first analysis of a space--time hybridizable discontinuous Galerkin method for the advection--diffusion problem on time-dependent domains.
Cesmelioglu, Aycil, Horvath, Tamas L., Kirk, Keegan L. A., Rhebergen, Sander   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

An Improved Algorithm for Indirect Time domain Analysis of Thin Wire Structures

Journal of Communications Software and Systems, 2012
The algorithm for an indirect time domain (TD) analysis using arbitrary frequency domain method is presented.In previous work, an optimized version of the indirect timedomain method based on adaptive sampling iterative algorithm used in combination with ...
Siniša Antonijević, Vicko Dorić, Dragan Poljak   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Reduced order feedback control equations for linear time and frequency domain analysis [PDF]

An algorithm was developed which can be used to obtain the equations. In a more general context, the algorithm computes a real nonsingular similarity transformation matrix which reduces a real nonsymmetric matrix to block diagonal form, each block of ...
Frisch, H. P.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Time–Frequency Domain Analysis of the Ground Vibration of an Elevated Railway and Study on the Elliptic Polarization Dispersion Characteristics of Rayleigh Waves

Computation
Elevated railways are a crucial component of railway lines, characterized by their widespread distribution, simple structure, and low cost, while actively promoting local economic development.
Shijie Liu, Yulan Song, Zhengping Liu, Zhe Liu, Qingling Du   +4 more
doaj   +1 more source

Impaired circadian heart rate variability in Parkinson's disease: a time-domain analysis in ambulatory setting. [PDF]

BMC Neurol, 2020
Arnao V, Cinturino A, Mastrilli S, Buttà C, Maida C, Tuttolomondo A, Aridon P, D'Amelio M.   +7 more
europepmc   +1 more source