Results 61 to 70 of about 36,626,105 (254)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
CSEE Journal of Power and Energy SystemsPower inverter adopting virtual synchronous generator (VSG) control can provide inertia support for distributed generation systems. However, it cannot take into account the dynamic regulation characteristics of frequency. Thus, when the system encounters
Hongwei Fang, Zhiwei Yu
doaj +1 more source
Fatigue life study of the door on the new-type 160 km/h railway box wagon
机车电传动, 2023 During train operation, influenced by track irregularity or random wind load, the vehicle body is continuously under the impact of random vibration loads, which will cause fatigue damage to the vehicle structure in severe cases. To ensure train operation
MA Chengcheng +3 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Terahertz Time Domain Spectrometer
, 2014 In the framework of the European Metrology Research Program Project NEW-07 “Microwave and Terahertz metrology for homeland security”, a Time Domain Spectrometer working up to about 3 THz has been realized.
OBERTO, LUCA, BISI, MARCO
core
Multi-domain product modelling: from requirements to cad and simulation tools. [PDF]
, 2009 Today, in a very competitive industrial context, different companies have difficulties to respect delays in design and manufacturing of multi-domain product.
OSTROSI, Egon +3 more
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Measurement of antennas and microwave components using time-domain reflectometry of a voltage impulse [PDF]
, 2011 Band-pass microwave systems such as ultra-wideband antennas are traditionally characterized in the frequency-domain through a vector network analyzer in an anechoic chamber.
Jonathan Scott +3 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Performance Bound Analysis of Analog Circuits in Frequency- and Time-Domain Considering Process Variations [PDF]
, 2013 In this article, we propose a new performance bound analysis of analog circuits considering process variations. We model the variations of component values as intervals measured from tested chips and manufacture processes.
ADOLFO ADAIR PALMA RODRIGUEZ +1 more
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