Results 71 to 80 of about 2,528,294 (311)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

An analytical and numerical analysis of several locally conformal FDTD schemes [PDF]

open access: yes, 1999
The virtues of the finite-difference time-domain (FDTD) method for the electromagnetic analysis of arbitrary complex metal and dielectric structures are well known.
Schneider, JB, Railton, CJ
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Distributed-memory parallelization of an explicit time-domain volume integral equation solver on Blue Gene/P [PDF]

open access: yes, 2012
Two distributed-memory schemes for efficiently parallelizing the explicit marching-on in-time based solution of the time domain volume integral equation on the IBM Blue Gene/P platform are presented.
Cheeseman, M, Bağcı, H, Al-Jarro, A
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Terahertz Time Domain Spectrometer

open access: yes, 2014
In the framework of the European Metrology Research Program Project NEW-07 “Microwave and Terahertz metrology for homeland security”, a Time Domain Spectrometer working up to about 3 THz has been realized.
OBERTO, LUCA, BISI, MARCO
core  

Mooring optimization design based on neural network and genetic algorithm

open access: yesZhongguo Jianchuan Yanjiu, 2017
[Objectives] In order to maintain the stability of the position of a ship, a mooring system is required to reduce the translational motion of floating structures.[Methods] Taking a pipe-laying vessel in the South China Sea as an example, it is possible ...
XU Xiaoying, ZHOU Pan, WANG Kuan
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Full-wave analysis of reverse saturable absorption in time-domain

open access: yes, 2018
An advanced full-wave time-domain numerical model for reverse saturable absorption (RSA) is presented and verified against established methods. Rate equations, describing atomic relaxations and excitation dynamics, are coupled to Maxwell equations by ...
Alexander V. Kildishev (1611955)   +1 more
core   +1 more source

A Novel Piecewise Linear Recursive Convolution Approach for Dispersive Media Using the Finite-Difference Time-Domain Method [PDF]

open access: yes, 2014
Two novel methods for implementing recursively the convolution betweenthe electric field and a time dependent electric susceptibility function inthe finite-difference time domain (FDTD) method are presented.
Giannakis, Iraklis   +2 more
core   +1 more source

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