Results 111 to 120 of about 84,673 (295)
Order parameter model for unstable multilane traffic flow
, 2000 We discuss a phenomenological approach to the description of unstable vehicle motion on multilane highways that explains in a simple way the observed sequence of the phase transitions "free flow -> synchronized motion -> jam" as well as the hysteresis in
A. Zerr +17 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A comparative reliability analysis of ETCS train radio communications [PDF]
, 2005 StoCharts have been proposed as a UML statechart extension for performance and dependability evaluation, and were applied in the context of train radio reliability assessment to show the principal tractability of realistic cases with this approach.
Hermanns, H., Jansen, D.N., Usenko, Y.S.
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Discrete Dynamics in Nature and Society, 2015 This study aimed to calibrate saturation flow rate (SFR) and start-up lost time (SLT) when developing signal timing. In current commonly used methods, SFR for one given lane is usually calibrated from many subjective adjustment factors and a fixed result.
Yi Zhao +4 more
doaj +1 more source
Properties of pedestrians walking in line - Fundamental diagrams
, 2011 We present experimental results obtained for a one-dimensional flow using high precision motion capture. The full pedestrians' trajectories are obtained.
A. Seyfried +5 more
core +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
An Improved General Motor Car-Following Model considering the Lateral Impact
Advances in Mechanical Engineering, 2015 We improve the typical GM car-following model. In order to describe the impacts of the lateral offset between the vehicles in car-following state, this paper proposes time distance to measure the drivers' attention of driving environment and uses ...
Pengfei Tao +7 more
doaj +1 more source