Results 101 to 110 of about 84,673 (295)
Towards a realistic microscopic description of highway traffic
, 2000 Simple cellular automata models are able to reproduce the basic properties of highway traffic. The comparison with empirical data for microscopic quantities requires a more detailed description of the elementary dynamics.
A Schadschneider +22 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Disaggregate Inter-Urban Mode Choice Models: A review of British Evidence with special Reference to Cross Elasticities. [PDF]
, 1997 The research reported in this paper forms part of EPSRC project GRK52522 entitled 'National Multi-Modal Travel Forecasts'. The principal aim of this project is to develop a set of national and regional travel demand forecasts by land-based modes.
Wardman, M.
core
Studi Delay Time Dan Time Headway Bus Tranjakarta Koridor IV
LOGISTIK, 2008 Tujuan dioperasikannya Bus Transjakarta (Tije) adalah memberikan jasa angkutan yang lebih cepat, nyaman, terjangkau bagi warga Jakarta. Namun dalam pengadaan itu sendiri juga banyak mengalami kendala terutama waktu kedatangannya yang cenderung lama padahal sudah cukup lama bus Transjakarta beroperasi.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Analysis of time headway distribution on suburban arterial
KSCE Journal of Civil Engineering, 2012 Vehicular time headway is of fundamental importance in traffic engineering. For any traffic simulation to effectively address traffic problems, accurate vehicle generation is essential. Previous researches on this subject have focused solely on the stochastic modeling of uninterrupted facilities.
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Journal of Advanced Transportation, 2018 Objective. This paper examines the effects of various measures of performance (MOP) selections on simulation model calibration performance, in terms of reflecting actual traffic conditions and vehicle interactions. Method.
Chen Wang, Chengcheng Xu
doaj +1 more source