Results 51 to 60 of about 38,021 (255)

Two-Dimensional Underdetermined DOA Estimation of Quasi-Stationary Signals using Parallel Nested Array [PDF]

Radioengineering, 2020
In this paper, a two dimensional underdetermined direction of arrival estimation (DOA) of quasi-stationary signals using a parallel nested array structure is investigated.
X. Y. Pan, Q. P. Xie, J. Y. Chen, S. P. Xiao   +3 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Deep Learning-Based Travel Time Estimation in Hiking with Consideration of Individual Walking Ability

Cybernetics and Information Technologies
Hiking is popular, but mountain accidents are serious problems. Accurately predicting hiking travel time is an essential factor in preventing mountain accidents.
Asako Mizuho, Tahara Yasuyuki, Ohsuga Akihiko, Sei Yuichi   +3 more
doaj   +1 more source

Robust Blind Algorithm for DOA Estimation Using TDOA Consensus

Acoustics
This paper proposes a robust blind algorithm for direction of arrival (DOA) estimation in challenging acoustic environments. The method introduces a novel Time Difference of Arrival (TDOA) consensus framework that effectively identifies and filters ...
Danilo Greco
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

An Error Analysis Method for Correlation-Based Parameter Estimators in Discrete-Time Signals Under Gaussian Noise

IEEE Access
In this study, we expand on a previously introduced method for computing the error statistics associated with estimating the time of arrival of a known signal in sampled data with additive white Gaussian noise (AWGN).
Chris Hall, Ivan Djordjevic
doaj   +1 more source

Position determination of acoustic source using higher-order spectral analysis for time of arrival estimation [PDF]

Scientific Technical Review, 2019
The localization of various acoustic sources in a battlefield (such as weapon rounds, mortars, rockets, mines, improvised explosive devices, vehicle-borne improvised explosive devices and airborne vehicles) nowadays has a significant history. In acoustic
Pokrajac Ivan P., Vračar Miodrag, Šević Tamara, Joksimović Vasilija   +3 more
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