Results 61 to 70 of about 38,021 (255)

A Novel Method for DOA and Time Delay Joint Estimation in Multipath OFDM Environment

International Journal of Antennas and Propagation, 2020
Joint time delay and direction of arrival estimation based on uniform linear arrays in Orthogonal Frequency Division Multiplexing (OFDM) systems has to face the problems posed by coherent multipath environments and high computational complexity.
Xiangzhi Li, Weijia Cui, Haiyun Xu, Bin Ba, Yankui Zhang   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Space-time division cluster DoA estimation algorithm based on UWA spread spectrum signal

Tongxin xuebao, 2022
To solve the problems of poor stability, low resolution, and performance degradation under low signal-to-noise ratio (SNR) of the direction of arrival (DoA) estimation, a space-time division cluster (STDC) DoA estimation algorithm was proposed for under ...
Feng ZHOU, Baosheng ZHANG, Wenbo ZHANG
doaj   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

TDOA, Frequency and Phase Offsets Estimation Taking Into Account Carrier Phase of Arrival [PDF]

Radioengineering, 2017
This paper deals with estimation of time difference of arrival (TDOA) and phase and frequency offsets between the channels in a receiving system with two distributed time synchronized, but phase and frequency unlocked channels.
M. Janjic, N. Vukmirovic, M. Eric
doaj  

A Hybrid Distance Estimation for Wireless Body Sensor Networks

International Journal of Distributed Sensor Networks, 2013
Wireless body area networks become a new research issue in recent years. In this paper, we propose hibernation and distance estimation schemes for wireless USB (WUSB) over wireless body area networks (WBAN) hierarchical protocol for body sensor networks (
Kyeong Hur, Won-Sung Sohn, Jae-Kyung Kim
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Fast Estimation Method of Space-Time Two-Dimensional Positioning Parameters Based on Hadamard Product

International Journal of Antennas and Propagation, 2018
The estimation speed of positioning parameters determines the effectiveness of the positioning system. The time of arrival (TOA) and direction of arrival (DOA) parameters can be estimated by the space-time two-dimensional multiple signal classification ...
Haiwen Li, Nae Zheng, Xiyu Song, Yinghua Tian   +3 more
doaj   +1 more source