Results 81 to 90 of about 311,579 (323)

High signal-to-noise ratio observations and the ultimate limits of precision pulsar timing

, 2011
We demonstrate that the sensitivity of high-precision pulsar timing experiments will be ultimately limited by the broadband intensity modulation that is intrinsic to the pulsar's stochastic radio signal. That is, as the peak flux of the pulsar approaches
Andrews, Backer, Backer, Bailes, Bailes, Bartel, Bhat, Boynton, Britton, Cairns, Cognard, Coles, Cordes, Cordes, Cordes, Davis, Dewey, Drake, Durdin, Foster, G. B. Hobbs, Groth, Groth, Groth, Gwinn, Gwinn, Gwinn, Gwinn, Gwinn, Gwinn, Hankins, Hankins, Hankins, Helfand, Helfand, Hellings, Hoaglin, Hobbs, Hobbs, Hotan, Hotan, Hotan, Hubert, Hyvarinen, Jenet, Jenet, Jenet, Johnson, Johnston, Karastergiou, Karastergiou, Kaspi, Kinkhabwala, Kramer, Kramer, Kramer, Kramer, Kramer, Kulkarni, Liu, Lyne, M. Bailes, Manchester, Manchester, Manchester, Matsakis, Navarro, P. Demorest, Petit, Rathnasree, Rickett, Rodin, S. Osłowski, Sallmen, Sandhu, Shannon, Smits, Staelin, Stairs, Staveley-Smith, Taylor, Taylor, Taylor, van Haasteren, van Straten, van Straten, van Straten, van Straten, van Straten, van Straten, Verbiest, Vivekanand, Vivekanand, W. van Straten, Wang, Weisberg, Yan, Yardley   +97 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Deep Learning-Based Travel Time Estimation in Hiking with Consideration of Individual Walking Ability

Cybernetics and Information Technologies
Hiking is popular, but mountain accidents are serious problems. Accurately predicting hiking travel time is an essential factor in preventing mountain accidents.
Asako Mizuho, Tahara Yasuyuki, Ohsuga Akihiko, Sei Yuichi   +3 more
doaj   +1 more source

Robust Blind Algorithm for DOA Estimation Using TDOA Consensus

Acoustics
This paper proposes a robust blind algorithm for direction of arrival (DOA) estimation in challenging acoustic environments. The method introduces a novel Time Difference of Arrival (TDOA) consensus framework that effectively identifies and filters ...
Danilo Greco
doaj   +1 more source

Space-time division cluster DoA estimation algorithm based on UWA spread spectrum signal

Tongxin xuebao, 2022
To solve the problems of poor stability, low resolution, and performance degradation under low signal-to-noise ratio (SNR) of the direction of arrival (DoA) estimation, a space-time division cluster (STDC) DoA estimation algorithm was proposed for under ...
Feng ZHOU, Baosheng ZHANG, Wenbo ZHANG
doaj   +2 more sources

A Novel Method for DOA and Time Delay Joint Estimation in Multipath OFDM Environment

International Journal of Antennas and Propagation, 2020
Joint time delay and direction of arrival estimation based on uniform linear arrays in Orthogonal Frequency Division Multiplexing (OFDM) systems has to face the problems posed by coherent multipath environments and high computational complexity.
Xiangzhi Li, Weijia Cui, Haiyun Xu, Bin Ba, Yankui Zhang   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

An Error Analysis Method for Correlation-Based Parameter Estimators in Discrete-Time Signals Under Gaussian Noise

IEEE Access
In this study, we expand on a previously introduced method for computing the error statistics associated with estimating the time of arrival of a known signal in sampled data with additive white Gaussian noise (AWGN).
Chris Hall, Ivan Djordjevic
doaj   +1 more source