Results 171 to 180 of about 44,209 (261)

Changes in Biologically Active Compounds During the Ripening Period in Selected Hungarian-Bred Sour Cherry Varieties (<i>Prunus cerasus</i> L.). [PDF]

Plants (Basel)
Ficzek G, Simon G, Gergely M, Mehmeti S, Krasniqi V, Mali-Gáspár E, Komma L, Vegvari G, Bujdosó G.   +8 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Early Developmental Regulation of Tyrosine Decarboxylase in Olive Fruits and Its Impact on Virgin Olive Oil Phenolics. [PDF]

J Agric Food Chem
Luaces P, Sánchez R, Expósito J, Pérez AG, Sanz C.   +4 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

<i>Cytokinin Oxidase/Dehydrogenase 1</i> (<i>FvCKX1</i>) Coordinates Receptacle Growth and Achene Maturation in Strawberry. [PDF]

Plants (Basel)
Tian Y, Ren L, Zhu Z, Chen Z, Yuan Y, Lv Y, Xin W, Wu C, Ma J, He J, Lin J, Liu Y, Xu T, Tang W.   +13 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ripening- and Season-Dependent Variation in Polyphenolic Compounds and the Antioxidant Capacity of Sour Cherry (<i>Prunus cerasus</i> L.). [PDF]

Antioxidants (Basel)
Pál A, Nagy R, Máthé E, Keczkó P, Sipos P.   +4 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Editorial: Advances in fruit-growing systems as a key factor of successful production, volume II. [PDF]

Front Plant Sci
Bujdoso G.
europepmc   +1 more source