Results 91 to 100 of about 14,827,936 (205)

Which Measures of Time Preference Best Predict Outcomes? Evidence from a Large-Scale Field Experiment [PDF]

open access: yes
Economists and psychologists have devised numerous instruments to measure time preferences and have generated a rich literature examining the extent to which time preferences predict important outcomes; however, we still do not know which measures work ...
Carpenter, Jeffrey P.   +3 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Tariffs, Time Preference, and the Current Account under Weakly Nonseparable Preferences. [PDF]

open access: yes
Incorporating weakly nonseparable preferences into the familiar time-preference model, we emphasize a role of steady-state welfare changes in determining the effect of permanent tariffs on the current account.TARIFFS ; SOCIAL WELFARE ...
Ikeda, S.
core  

NEW PATTERNS IN SCHEDULING WORKING TIME [PDF]

open access: yesManagement & Marketing, 2010
Flexible work arrangements should focus on providing employees with more options for when and how they do their work. Organizations can provide a suite of flexible options to enable employees to choose the arrangements that best balance their work with ...
Claudiu George BOCEAN   +1 more
doaj  

Conceptualizing Time Preference: A Life-History Analysis

open access: yesEvolutionary Psychology, 2014
Life-history theory (LHT) has drawn upon the concept of “time preference” as a psychological mechanism for the development of fast and slow strategies. However, the conceptual and empirical nature of this mechanism is ill-defined.
Lee T. Copping   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A theory of endogenous time preference, and discounted utility anomalies [PDF]

open access: yes
We explain essentially all known discounted utility anomalies as artefacts of the optimizing behavior of an individual with a time- separable utility function, who perceives a good as a source of a stochastic consumption stream, and believes that she can
Svetlana Boyarchenko   +1 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Risk aversion under preference uncertainty [PDF]

open access: yes, 2010
We show that if an agent is uncertain about the precise form of his utility function, his actual relative risk aversion may depend on wealth even if he knows his utility function lies in the class of constant relative risk aversion (CRRA) utility ...
Lucas, A.; id_orcid   +8 more
core   +1 more source

Patient preferences for biologic and biosimilar osteoporosis treatments in colombia

open access: yes, 2020
Purpose: Teriparatide is used to treat patients with established osteoporosis but is often reserved for patients who have inadequate response to antiresorptive therapy. Biosimilar teriparatide, which is believed to have efficacy and safety similar to the
Hauber B.   +7 more
core   +1 more source

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