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Lege, preferinţă de timp şi criminalitate
Sociologie Românească, 2010 This article focuses on the theoretical research of the nature and the dynamics of the mechanisms and relations between the political system, legislative system, social time preference and the criminal phenomenon.
Alexandru Odea
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Budget allocation and the revealed social rate of time preference for health [PDF]
Appropriate decisions based on cost-effectiveness evaluations of health care technologies depend upon the cost-effectiveness threshold and its rate of growth as well as some social rate of time preference for health. The concept of the cost-effectiveness
Mike Paulden, Karl Claxton
core
It will be worth it, in the end: a model of naturalistic intertemporal choice
Frontiers in PsychologyIntertemporal choices, which involve consequences spread over time, often display a bias toward short-term rewards, which was recognized in ancient Greek philosophy as “akrasia.” This bias is nowadays often modelled via hyperbolic discounting models ...
Philip Newall +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
, 1924 Cover title.; At head of title: White Train souvenir publication, Canberra, Sat. 23rd Oct. - Queanbeyan, 25th-26th Oct.; Electronic reproduction. Canberra, A.C.T.
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Individuals' Rates of Time Preference for Life-Saving Programs in Developing Countries: Results from a Multi-Country Study [PDF]
Individuals' time preferences for mortality reductions are measured in six Less Developed Countries in Africa, Eastern Europe, and Asia using the contingent valuation method.
Christine Poulos, Dale Whittington
core
Real income growth and revealed preference inconsistency [PDF]
, 2001 If a smooth demand function violates the strong axiom of revealed preference, the income and prices can follow a cycle and returm to their starting values even though real income is always rising. We show how real income growth along the "worst" revealed
Jerison, Michael, Jerison, David
core +1 more source