Results 231 to 240 of about 17,947,053 (276)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Time-restricted eating in Alzheimer's disease: TREAD pilot trial design. [PDF]

Contemp Clin Trials Commun
Racette SB, Gunning JA, Eagan DE, Zaniletti I, Smith TL, DeCuna CJ, Hettiwatte YS, Demeke MT, Khan NA, Aliskevich EL, Krell-Roesch J, Geda YE.   +11 more
europepmc   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Effects of Nordic Walking Combined with High-Protein Intake and Time-Restricted Eating on Muscle-Related Outcomes in Postmenopausal Women: A Three-Arm Randomized Controlled Trial. [PDF]

Nutrients
Yang Y, Zhu Y, Ossowski Z.
europepmc   +1 more source

Effects of combining exercise with a 16:8 time-restricted eating protocol on body composition and glucose-lipid metabolism in adults: a systematic review and meta-analysis. [PDF]

Front Nutr
Liu H, Hu G, Ma X.
europepmc   +1 more source

Understanding Participants' and Health Professionals' Perceptions and Experiences of Time-Restricted Eating: A Systematic Review of Qualitative Evidence. [PDF]

Obes Rev
Fernández-Rodríguez R, Boira-Nacher B, Visier-Alfonso ME, Torres-Costoso A, Martínez-Vizcaíno V, Ruiz JR.   +5 more
europepmc   +1 more source

Post-intervention sustainability of time-restricted eating versus caloric restriction: a secondary analysis. [PDF]

Int J Obes (Lond)
Chen DA, Pena RH, Oldenburg N, Wang Q, Helgeson E, Yentzer B, Taddese A, LaPage N, Manoogian ENC, Panda S, Chow LS.   +10 more
europepmc   +1 more source

Calorie Restriction With or Without Time-Restricted Eating in Weight Loss

New England Journal of Medicine, 2022
The long-term efficacy and safety of time-restricted eating for weight loss are not clear.We randomly assigned 139 patients with obesity to time-restricted eating (eating only between 8:00 a.m. and 4:00 p.m.) with calorie restriction or daily calorie restriction alone.
Hua He, Jiang He, Changwei Li
exaly   +9 more sources

Design and Implementation of a Time-Restricted Eating Intervention in a Randomized, Controlled Eating Study

Nutrients, 2023
The efficacy of time-restricted eating for weight loss has not been established, as prior studies were limited by a lack of controlled isocaloric designs. This study describes the design and implementation of interventions in a controlled eating study evaluating time-restricted eating.
May Thu Thu Maw, Lawrence J. Appel, Scott J. Pilla   +2 more
exaly   +4 more sources