Results 101 to 110 of about 11,323,677 (336)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Conditional oscillation of half-linear Euler-type dynamic equations on time scales
Electronic Journal of Qualitative Theory of Differential Equations, 2015 We investigate second-order half-linear Euler-type dynamic equations on time scales with positive periodic coefficients. We show that these equations are conditionally oscillatory, i.e., there exists a sharp borderline (a constant given by the ...
Petr Hasil, J. Vítovec
doaj +1 more source
Links between ocean properties, ice cover, and plankton dynamics on interannual time scales in the Canadian Arctic Archipelago [PDF]
, 2013 James M. Hamilton +2 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
New results for time reversed symplectic dynamic systems and quadratic functionals
Electronic Journal of Qualitative Theory of Differential Equations, 2012 In this paper, we examine time scale symplectic (or Hamiltonian) systems and the associated quadratic functionals which contain a forward shift in the time variable.
Roman Simon Hilscher, Petr Zemanek
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Qualitative aspects of Volterra integro-dynamic system on time scales
Electronic Journal of Qualitative Theory of Differential Equations, 2013 This paper deals with the resolvent, asymptotic stability and boundedness of the solution of time-varying Volterra integro-dynamic system on time scales in which the coefficient matrix is not necessarily stable.
Vasile Lupulescu +2 more
doaj +1 more source
Short-Time Existence for Scale-Invariant Hamiltonian Waves
, 2005 We prove short-time existence of smooth solutions for a class of nonlinear, and in general spatially nonlocal, Hamiltonian evolution equations that describe the self-interaction of weakly nonlinear scale-invariant waves. These equations include ones that
Hunter, John K.
core
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Time scales and the asymptotics for the solutionsof discrete adiabatic oscillators
Моделирование и анализ информационных систем, 2011 We develop a method of averaging for the study of linear systems of dynamic equations on time scales. We use the obtained results to construct the asymptotics for the solutions of some equations of discrete adiabatic oscillators.
P. N. Nesterov
doaj