Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Integral inequalitys for partial dynamic equations on time scales
Electronic Journal of Differential Equations, 2012 The aim of the present paper is to study some basic qualitative properties of solutions of some partial dynamic equations on time scales. A variant of certain fundamental integral inequality with explicit estimates is used to establish our results.
Deepak B. Pachpatte
doaj
Existence and Exponential Stability of Periodic Solution of High‐Order Hopfield Neural Network with Delays on Time Scales [PDF]
, 2009 Yongkun Li, Lili Zhao, Ping Liu
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Examining dependencies among different time scales in episodic memory - an experience sampling study. [PDF]
Front Psychol, 2023 Yim H +5 more
europepmc +1 more source
Simulation Algorithms With Exponential Integration for Time-Domain Analysis of Large-Scale Power Delivery Networks [PDF]
, 2016 Hao Zhuang +7 more
openalex +1 more source
Stability of Simultaneously Triangularizable Switched Linear Systems on Time Scales [PDF]
, 2021 John E. Miller, Ian Gravagne
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Cosmological perturbations in inflationary models with anisotropic space-time scaling in a Lifshitz background [PDF]
, 2013 Mohsen Alishahiha +3 more
openalex +1 more source