Results 41 to 50 of about 1,042 (208)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
A novel FPGA-based time-to-digital converter featuring machine learning-aided self-calibration
Intelligent Systems with ApplicationsTime-to-digital converters (TDCs) implemented on Field-Programmable Gate Arrays (FPGAs) encounter significant challenges in achieving high precision. Unlike Application-Specific Integrated Circuits, FPGA-based TDCs must depend on standard logic elements ...
Arash Amini Bardpareh +8 more
doaj +1 more source
Sensors, 2020 This paper presents a reconfigurable time-to-digital converter (TDC) used to quantize the phase of the impedance in electrical impedance spectroscopy (EIS).
Sounghun Shin +7 more
doaj +1 more source
A 0.002‐mm2 8‐bit 1‐MS/s low‐power time‐based DAC (T‐DAC)
IET Circuits, Devices and Systems, 2021 Digital‐to‐analogue converters (DACs) are essential blocks for interfacing the digital environment with the real world. A novel architecture, using a digital‐to‐time converter (DTC) and a time‐to‐voltage converter (TVC), is employed to form a low‐power ...
Ali H. Hassan +4 more
doaj +1 more source
Research of a carry chain TDC and its tap method
Dianzi Jishu Yingyong, 2022 A time to digital converter(TDC) is implemented using carry chains in Xilinx Kinex-7 FPGA. FPGA-TDC is calibrated bin-by-bin through the code density calibration method.
Li Haitao +4 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Digital twin based monitoring and control for DC-DC converters
Nature Communications, 2023 The monitoring and control of DC-DC converters have become key issues since DC-DC converters are gradually playing increasingly crucial roles in power electronics applications such as electric vehicles and renewable energy systems.
Zhongcheng Lei +4 more
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Area-Efficient Mixed-Signal Time-to-Digital Converter Integration for Time-Resolved Photon Counting
SensorsDigital histogram generation for time-resolved measurements with single-photon avalanche diode (SPAD) sensors requires the storage of many timestamp signals.
Sergio Moreno +3 more
doaj +1 more source